Application of the Photocatalytic Chemistry of Titanium Dioxide to Disinfection and the Killing of Cancer Cells

Blake, Daniel M.; Maness, Pin‐Ching; Huang, Zuhao; Wolfrum, Edward J.; Huang, Jie; Jacoby, William A.

doi:10.1080/03602549909351643

Cited by 538 publications

(313 citation statements)

References 122 publications

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“…Blake et al described that the efficiency of photocatalysts varies with the type of microorganism. They suggested that the efficiency of photocatalysts is influenced by the complexity and thickness of the cell wall 23) . Kühn et al reported that the reduction efficiencies decreased in order of E. coli>P. aeruginosa>S. aureus>E. faecium>C. albicans.…”

Section: Discussionmentioning

confidence: 99%

Antimicrobial and antifungal effects of tissue conditioners containing a photocatalyst

et al. 2011

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This study examined the antimicrobial/antifungal ability of a tissue conditioner containing a photocatalyst for Escherichia coli, Streptococcus mutans, Staphylococcus aureus and Candida albicans. The photocatalyst was mixed with tissue conditioners powders at concentrations of 0, 10, 15, and 20 wt%. Tissue conditioners powders containing a photocatalyst were mixed with liquid to make test specimens. Test specimens inoculated by each microorganism were irradiated by ultraviolet light for 0-, 2-and 4 hours. The antimicrobial/antifungal effects were evaluated by the CFU technique. The CFU values of each microorganism for tissue conditioners containing a photocatalyst showed significant decrease following UV-irradiation. The improvement in antimicrobial/antifungal effects was concomitant with the increase of the mixing ratio and the irradiation time. Therefore, the results indicated that tissue conditioners containing a photocatalyst might have photocatalytic ability.

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Section: Discussionmentioning

confidence: 99%

Antimicrobial and antifungal effects of tissue conditioners containing a photocatalyst

et al. 2011

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“…GNRs are generally more resistant to disinfectants than GPCs due to outer membrane barrier, but the resistant mechanism is not well characterized. Although the microbicidal activity by photocatalysis has not been studied thoroughly and the mechanism of the bactericidal process is still unknown [27,39], there are some suggestions and evidences for the steps leading to cell inactivation. TiO 2 photocatalysis generates various ROS as follows [24].…”

Section: Bactericidal Activity Of Photocatalysis By Tio 2 -Coated Glassmentioning

confidence: 99%

Broad Spectrum Microbicidal Activity of Photocatalysis by TiO2

et al. 2013

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Photocatalytically active titanium dioxide (TiO 2 ) is widely used as a self-cleaning and self-disinfecting material in many applications to keep environments biologically clean. Several studies on the inactivation of bacteria and viruses by photocatalytic reactions have also been reported; however, only few studies evaluated the spectrum of the microbicidal activity with photocatalysis for various species. There is a need to confirm the expected OPEN ACCESSCatalysts 2013, 3 311 effectiveness of disinfection by photocatalysis against multidrug-resistant bacteria and viruses. In this study, microbicidal activity of photocatalysis was evaluated by comparing the inactivation of various species of bacteria and viruses when their suspensions were dropped on the surface of TiO 2 -coated glass. Gram-positive bacteria, e.g., methicillin-resistant Staphylococcus aureus, vancomycin-resistant Enterococcus faecalis, and penicillin-resistant Streptococcus pneumoniae, were easily inactivated by photocatalysis, whereas some gram-negative bacteria, e.g., Escherichia coli and multidrug-resistant Pseudomonas aeruginosa, were gradually inactivated by photocatalysis. Influenza virus, an enveloped virus, was significantly inactivated by photocatalysis compared with feline calicivirus, a non-enveloped virus. The effectiveness of microbicidal activity by photocatalysis may depend on the surface structure. However, they are effectively inactivated by photocatalysis on the surface of TiO 2 -coated glass. Our data emphasize that effective cleaning and disinfection by photocatalysis in nosocomial settings prevents pathogen transmission.

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“…Therefore, enamel demineralization is considered a bacterial infectious disease. Streptococci bacteria are the earliest colonizers of the teeth (Blake et al, 1999), and it is generally accepted that Streptococcus mutans is the primary causative agent of dental caries. Mutans streptococci produce glucosyltransferase, an enzyme that plays a role in the catalysis of sucrose (Arslan et al, 2012).…”

Section: Introductionmentioning

confidence: 99%

Photocatalytic antimicrobial effect of TiO2 anatase thin-film–coated orthodontic arch wires on 3 oral pathogens

Özyıldız¹,

Uzel²,

Hazar³

et al. 2014

Turk J Biol

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The aim of this study was to introduce antimicrobial activity to stainless steel orthodontic arch wires by coating them with TiO2 in anatase form. Stainless steel (0.016 × 0.022 inch), D-rect (0.016 × 0.022 inch), and multistranded hammered retainer wires (0.014 × 0.018 inch) were coated with TiO2 anatase by the sol-gel dip coating method. The wires were assessed for their photocatalytic antimicrobial activity against Streptococcus mutans, Candida albicans, and Enterococcus faecalis. After illumination under UVA (315– 400 nm) at 1.0 mW/cm2 for 1 h, the reduction efficiencies of the anatase-coated arch wires were calculated by using colony-forming unit counts. All anatase-coated arch wires showed remarkable inhibitor effects against the test microorganisms under UVA. The most efficient wire on S. mutans was the stainless steel wire, with a 99.99% reduction in growth, but multistranded hammered retainer wire was the most active against both C. albicans and E. faecalis, with 98.0% and 91.68% reduction rates, respectively. TiO2-coated arch wires exposed to UVA illumination showed significant antimicrobial activity when compared with uncoated samples and coated, but not UVA-exposed, samples. Our results suggest that the antimicrobial effect of TiO2-coated arch wires in long-lasting orthodontic treatments would be beneficial for the prophylaxis of caries

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Application of the Photocatalytic Chemistry of Titanium Dioxide to Disinfection and the Killing of Cancer Cells

Cited by 538 publications

References 122 publications

Antimicrobial and antifungal effects of tissue conditioners containing a photocatalyst

Antimicrobial and antifungal effects of tissue conditioners containing a photocatalyst

Broad Spectrum Microbicidal Activity of Photocatalysis by TiO2

Photocatalytic antimicrobial effect of TiO2 anatase thin-film–coated orthodontic arch wires on 3 oral pathogens

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