Application of the extractive alkylation technique to the pentafluorobenzylation of morphine (a heroin metabolite) and surrogates, with special reference to the quantitative determination of plasma morphine levels using mass fragmentography

Determination of morphine in serum and cerebrospinal fluid by gas chromatography and selected ion monitoring after reversed-phase column extraction

“…Assessment of morphine after extraction by liquid chromatography with ultraviolet as well as electrochemical detection has been described [ 11-141. Gas chromatography combined with mass spectrometry offers a highly specific and sensitive method and is a most suitable assay to obtain an unequivocal identification of morphine [15][16][17][18][19][20][21][22][23] . …”

Determination of morphine in serum and cerebrospinal fluid by gas chromatography and selected ion monitoring after reversed-phase column extraction

“…Assessment of morphine after extraction by liquid chromatography with ultraviolet as well as electrochemical detection has been described [ 11-141. Gas chromatography combined with mass spectrometry offers a highly specific and sensitive method and is a most suitable assay to obtain an unequivocal identification of morphine [15][16][17][18][19][20][21][22][23] . …”

Determination of morphine in serum and cerebrospinal fluid by gas chromatography and selected ion monitoring after reversed-phase column extraction

“…Assessment of morphine after extraction by liquid chromatography with ultraviolet as well as electrochemical detection has been described [ 11-141. Gas chromatography combined with mass spectrometry offers a highly specific and sensitive method and is a most suitable assay to obtain an unequivocal identification of morphine [15][16][17][18][19][20][21][22][23] . …”

Determination of morphine in serum and cerebrospinal fluid by gas chromatography and selected ion monitoring after reversed-phase column extraction

“…Assessment of morphine after extraction by liquid chromatography with ultraviolet as well as electrochemical detection has been described [ 11-141. Gas chromatography combined with mass spectrometry offers a highly specific and sensitive method and is a most suitable assay to obtain an unequivocal identification of morphine [15][16][17][18][19][20][21][22][23] . …”