Eur. J. Chem. volume 3, issue 3, P279-282 2012 DOI: 10.5155/eurjchem.3.3.279-282.630
Parisa Gholamzadeh, Ghodsi Mohammadi Ziarani, Alireza Badiei, Zohreh Bahrami
Abstract:

An efficient and green condensation reaction is developed for the synthesis of (E)-arylidene-1,3-dihydroindole-2-ones; (1), using heterogeneous nanoporous acid catalyst of SBA-Pr-SO3H with pore size, 6 nm in solvent free condition. Arylidene-1,3-dihydroindole-2-ones have many pharmaceutical properties such as Tyrosin kinase inhibiton. This method has the advantages of short reaction time, isolation ease of the products, excellent yields and recyclable catalyst. Oxindole SBA-Pr-SO3H Green synthesis Solvent free reaction Tyrosin kinase inhibitor Arylidene-1,3-dihydroindole-2-ones

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