Application of manure containing tetracyclines slowed down the dissipation of tet resistance genes and caused changes in the composition of soil bacteria

Fifteen-Year Application of Manure and Chemical Fertilizers Differently Impacts Soil ARGs and Microbial Community Structure

“…Among these phyla, Actinobacteria show diverse antibiotic resistance, as they produce antibiotics, strongly promoting an increase and enrichment of the resistome (Su et al, 2015). A previous study demonstrated that manure application could induce a significant selective advantage for ARGs affiliated with the Micromonosporaceae family (Xiong et al, 2018). Another study showed that the genera Bacillus and Mycobacterium were possible bacterial pathogen hosts of ARGs that were enriched in a tetracycline-added soil treatment (Xia et al, 2019).…”

PCR DETECTION OF ENCODING TETRACYCLINE RESISTANCE tetC GENE IN THE BACTERIA OF TECHNOGENIC ECOTOPES

“…В настоящее время в составе хромосом, плазмид и транспозонов микроорганизмов идентифицировано более 46 генов, детерминирующих устойчивость к тетрациклину, доксициклину, окситетрациклину и хлортетрациклину. Мобильная природа tet генов частично объясняет их широкое распространение среди многих видов бактерий [Roberts et al, 2016;Xiong et al, 2018].…”

Variations of antibiotic resistance profiles in chickens during administration of amoxicillin, chlortetracycline and florfenicol

“…; Xiong et al . ). In China, relatively low concentrations of sulphonamides and macrolides and relatively high concentrations of fluoroquinolones and tetracyclines were detected in the sediments of the Yellow River, Hai River and Liao River (Zhou et al .…”

“…These levels antibiotics are positively correlated with their relative abundance in animal feeds (Xiong et al . b).…”

“…This extensive use of antibiotics has also increased the stress on the agricultural environment since antibiotic resistant bacteria and ARGs are also frequently present in water, sediments, soils and animals (Qiao et al 2018). For example, manure field applications or long-term wastewater irrigation water generated from antibiotic-treated animals significantly increase ARG abundance in farm soils Xiong et al 2018a). In China, relatively low concentrations of sulphonamides and macrolides and relatively high concentrations of fluoroquinolones and tetracyclines were detected in the sediments of the Yellow River, Hai River and Liao River (Zhou et al 2011).…”