Biomed. Chromatogr.
 1999
DOI: 10.1002/(sici)1099-0801(199904)13:2<155::aid-bmc851>3.0.co;2-6
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Application of fluorimetry to the analysis of Naproxen and its complexation with modified β-cyclodextrins

Itziar Vélaz
1
,
Miguel Sánchez
2
,
Arantza Zornoza
3
et al.
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Cited by 8 publications

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“…The stability constants of the naproxen complexes with b-CD at several temperatures and in acid medium (12) are considerably higher than those calculated for NAB in this work. In the case of HPb-CD and Mb-CD complexes with naproxen at pH 2 and 25°C (16), the results are also superior to those of NAB and in the same grade of increase.…”
Section: And the Plot Of [Mb-cd]/[1-(f O /F)] Vs [Mb-cd] Is Also Linearmentioning
confidence: 75%
“…It is possible to compare this value with that obtained for naproxen at pH 2 because of their similar structures. At pH 2, naproxen is in its non-ionized form, as is nabumetone; the quantum yield of the former obtained by us in these conditions is 0.2 (16).…”
Section: Spectro¯uorimetric Characteristicsmentioning
confidence: 99%
See 1 more Smart Citation
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…The stability constants of the naproxen complexes with b-CD at several temperatures and in acid medium (12) are considerably higher than those calculated for NAB in this work. In the case of HPb-CD and Mb-CD complexes with naproxen at pH 2 and 25°C (16), the results are also superior to those of NAB and in the same grade of increase.…”
Section: And the Plot Of [Mb-cd]/[1-(f O /F)] Vs [Mb-cd] Is Also Linearmentioning
confidence: 75%
“…It is possible to compare this value with that obtained for naproxen at pH 2 because of their similar structures. At pH 2, naproxen is in its non-ionized form, as is nabumetone; the quantum yield of the former obtained by us in these conditions is 0.2 (16).…”
Section: Spectro¯uorimetric Characteristicsmentioning
confidence: 99%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…Murillo et al [9] suggested the use 2 M pyridine in chlorofrom for the spectrometric analysis of naproxen, salicylate and salicylamide by measurement at λ ex /λ em =270/339, λ ex /λ em =307/440, λ ex /λ em =299/410 nm and following calculation of derivative spectra. Velaz et al [10] studied the complexation of naproxen in tablets, several organic and aqueous solutions with β-cyclodextrin, methyl β cyclodextrin or hydroxyl β-cyclodextrin applying fluorometry at λ ex =280 nm and λ em =348-357 nm.…”
Section: Uv-spectrometrymentioning
confidence: 81%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…Several methods involving either spectroscopic or chromatographic techniques for the determination of naproxen in pharmaceutical preparations and biological fluids have been proposed. [10][11][12][13][14][15][16] Cline Love and Weinberger 2 have found that intense RTP signals from a naproxen-sodium dodecyl sulfate (SDS) system using Tl(I) as heavy atom can be obtained. On the other hand, these authors concluded that poorly resolved RTP spectra of naproxen are obtained in the presence of both b-CD and 1,2-dibromoethane.…”
Section: Introductionmentioning
confidence: 99%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
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