volume 269, issue 2, P329-342 2004
DOI: 10.1016/j.ijpharm.2003.09.028
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Abstract: Pellets of a wide range of mechanical properties were produced by the process of extrusion and spheronisation using various formulation factors. A range of mechanical properties from a simple fracture load to detailed load/displacement curves obtained when pellets were subjected to diametral compression test and a bed of pellets was compacted, were used to provide measure of tensile strength, deformability, linear strain, elastic modulus, yield and shear strength. Such conventional techniques resulted in irrev…

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