Apparent Protein-Losing Enteropathy Associated With Giardiasis

Malabsorption in Giardiasis

“…Infection with Giardia may be associated with clinical and/or laboratory features suggestive of malabsorption, the extent of which is variable. This has been observed in children (12)(13)(14)(15)(16)(17)(18)(19)(20)(21)(22), and in adults (21, 23 -32). Geographically, giardiasis-associated malabsorption in adults has a wider distribution than that associated with tropical sprue (32).…”

“…An increased number of intraepithelial lympho-;. cytes has been observed in the small bowel mucosa of man (22,30,65) and rodents (67,71) infected with Giardia. These lymphocytes become engaged in the defense of the parasite or other antigen (65,72,73).…”

Giardiasis with Protein‐Losing Enteropathy

“…The illness resolved after metronidazole therapy. PLE was presumed, but was not documented (9). A 3year-old male child with 2 weeks of vomiting and I day of diarrhea had PLE confirmed by a SICrlabeled albumin excretion study.…”

Evaluation of Paediatric Patients with Protein Losing Enteropathy: A Single Centre Experience

“…Malabsorption is a well-known complication of giardiasis, but PLE is not common. It is considered that mucosal damage of the small intestine by giardia results in PLE (21). It has been reported in the literature that treatment with metronidazole alone as monotherapy is successful in the treatment of giardiasis (21)(22)(23).…”

“…It is considered that mucosal damage of the small intestine by giardia results in PLE (21). It has been reported in the literature that treatment with metronidazole alone as monotherapy is successful in the treatment of giardiasis (21)(22)(23). In our study, we detected that three cases (2, 2.5 and 9 years old) that were admitted with generalized body swelling had giardiasis.…”