volume 33, issue 10, P896-903 2018
DOI: 10.1590/s0102-865020180100000004
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Abstract: To investigate the apoptotic mechanisms in rabbits with blast-induced acute lung injury (ALI). Methods: A total of 40 rabbits were randomly divided into a blank control group (A, n=10) and an experimental group (EXP, n=30). Explosion-induced chest-ALI models were prepared and sampled at different time points (4, 12, and 24h after modeling, T1-T3) to test the lung dry weight/wet weight ratio (W/D) and arterial oxygen pressure (PaO 2), apoptosis of lung tissue by the TUNEL assay, and Caspase-3, Bax, and Bcl-2 le…

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