Apigetrin ameliorates doxorubicin prompted testicular damage: biochemical, spermatological and histological based study
Muhammad Umar Ijaz,
Saba Yaqoob,
Ali Hamza
et al.
Abstract:Doxorubicin (DOX) is a highly effective, commonly prescribed, potent anti-neoplastic drug that damages the testicular tissues and leads to infertility. Apigetrin (APG) is an important flavonoid that shows diverse biological activities. The present research was designed to evaluate the alleviative role of APG against DOX-induced testicular damages in rats. Forty-eight adult male albino rats were randomly distributed into 4 groups, control, DOX administered (3 mgkg−1), DOX + APG co-administered (3 mgkg−1 of DOX;… Show more
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