1995
DOI: 10.1055/s-2007-1013800
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Abstract: A case of aortic valve replacement for aortic insufficiency complicated with enterococcal endocarditis in a patient with systemic lupus erythematosus (SLE) is described. The cardiac complications of SLE may involve the endocardium, myocardium, pericardium, and coronary vessels. Steroids which are used for treatment probably increase the incidence of valve incompetence. Aortic insufficiency or infective endocarditis complicating Libman-Sacks endocarditis is rarely observed and may require valve replacement. Ech… Show more

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Cited by 6 publications
(3 citation statements)
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“…This may be important because long-term use of corticosteroids, a common treatment for patients with SLE, may predispose them to bacterial infections. [29][30][31][32] Conversely, steroid use can result in decreased size and number of Libman-Sacks lesions, which may decrease the risk of IE. 12 However, because steroid healing leads to fibrotic and retracted leaflet tissue, the risk of valvular dysfunction may, paradoxically, be increased.…”
mentioning
confidence: 99%
“…This may be important because long-term use of corticosteroids, a common treatment for patients with SLE, may predispose them to bacterial infections. [29][30][31][32] Conversely, steroid use can result in decreased size and number of Libman-Sacks lesions, which may decrease the risk of IE. 12 However, because steroid healing leads to fibrotic and retracted leaflet tissue, the risk of valvular dysfunction may, paradoxically, be increased.…”
mentioning
confidence: 99%
“…At this time, not enough data are available that indicate that stenoids or other immune suppression therapy is beneficial in the treatment of valvular involvement associated with SLE. Valve replacement has regularly been indicated in patients with symptomatic valve disease and with clinical and hemodynamic 7,28,29,30 , although morbidity associated with valve replacement in patients with lupus has been considered twice as high as in patients without lupus 10 , being closely linked to acute renal failure 7,28 . Recently, Morin et al 31 reviewed 25 cases of mitral failure secondary to SLE requiring valve replacement.…”
Section: Libman -Sacks Endocarditis and Valvular Heart Diseasementioning
confidence: 99%
“…The cardiac complications of SLE may involve the endocardium, myocardium, and pericardium. 58 The heart may become involved, with verrucous endocarditis of the mitral valve (Libman-Sacks disease). Other involvements of the heart include aortitis with dissection, left ventricular thrombosis, left ventricular hypertrophy, left ventricular aneurysm, myocardial infarction, pericardial effusion, fibrous endocarditis, mitral valve prolapse, acute hemorrhagic myocarditis, and cardiac rupture.…”
Section: Systemic Lupus Erythematosusmentioning
confidence: 99%