Antiviral Activity of Secondary Metabolites Produced by Streptomyces Species Isolated From Egyptian Soil.

Gaied, HebaAliAbdEl

doi:10.21474/ijar01/4227

IJAR

2017

DOI: 10.21474/ijar01/4227

|View full text |Cite

Antiviral Activity of Secondary Metabolites Produced by Streptomyces Species Isolated From Egyptian Soil.

HebaAliAbdEl Gaied¹

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2023

Publication Types

Select...

Article1

Relationship

Self Cite0

Independent1

Authors

Journals

Cited by 1 publication

References 23 publications

(27 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

Formulation Development and Evaluation of Dextran Nanoparticles Enclosed with Recombinant Typhoid (Ty21a) Antigen

R.,

V. B.

2023

ijnrph

View full text Add to dashboard Cite

Developing efficacious vaccines for Typhoid fever continues to be a paramount concern in global health, particularly in areas with a significant prevalence of the illness. This research focused on the synthesis, refinement, and analysis of recombinant Typhoid (Ty21a) antigen-encapsulated Eudragit-coated dextran nanoparticles. These nanoparticles function as an innovative platform for delivering the Ty21a antigen, which has the potential to enhance vaccination durability and effectiveness. The synthesis process was methodically adjusted to get optimal nanoparticle size, shape, and surface qualities by manipulating several formulation factors. The physicochemical evaluation verified the generation of precisely specified nanoparticles that effectively encapsulate the Ty21a antigen. The in vitro release assays shown that the Eudragit-coated nanoparticles can release antigens in a sustained and regulated manner, suggesting that they have the ability to provide prolonged immune activation. This study demonstrates the potential of using recombinant Typhoid antigen-encapsulated Eudragit-coated dextran nanoparticles as a promising platform for advanced vaccines. This platform offers improved ability to stimulate an immune response and controlled delivery of the antigen. These findings have significant implications for global health efforts focused on preventing Typhoid fever.

show abstract

Formulation Development and Evaluation of Dextran Nanoparticles Enclosed with Recombinant Typhoid (Ty21a) Antigen

R.,

V. B.

2023

ijnrph

View full text Add to dashboard Cite

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

hi@scite.ai

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Antiviral Activity of Secondary Metabolites Produced by Streptomyces Species Isolated From Egyptian Soil.

Cited by 1 publication

References 23 publications

Formulation Development and Evaluation of Dextran Nanoparticles Enclosed with Recombinant Typhoid (Ty21a) Antigen

Formulation Development and Evaluation of Dextran Nanoparticles Enclosed with Recombinant Typhoid (Ty21a) Antigen

Contact Info

Product

Resources

About