Antiviral Activity of Eight Commonly Used Medicinal Plants in Taiwan

Chiang, Lien-Chai; Cheng, Hua-Yew; Liu, Mei-Chi; Chiang, Wen Chin; Lin, Chun‐Ching

doi:10.1142/s0192415x03001582

Cited by 13 publications

(8 citation statements)

References 20 publications

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“…In fact, quercetin is seen as a universal suppressor of the accumulation and activation of immune cells, which prevents chronic inflammation [31,32]. Quercetin relaxes airway smooth muscle and potentiates β-agonist-induced relaxation via dual phosphodiesterase inhibition of purified phosphatidylinositol-specific phospholipase (CPLCβ) and phosphodiesterase type 4 inhibitor (PDE4) [33]. Quercetin has exerted strong anti-pathogenic effects against several causal agents of upper respiratory tract infection in vitro studies [34].…”

Section: Quercetinmentioning

confidence: 99%

The upshot of Polyphenolic compounds on immunity amid COVID-19 pandemic and other emerging communicable diseases: An appraisal

Khalil

Tazeddinova

2020

Nat. Prod. Bioprospect.

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Polyphenols are a large family of more than 10,000 naturally occurring compounds, which exert countless pharmacological, biological and physiological benefits for human health including several chronic diseases such as cancer, diabetes, cardiovascular, and neurological diseases. Their role in traditional medicine, such as the use of a wide range of remedial herbs (thyme, oregano, rosemary, sage, mint, basil), has been well and long known for treating common respiratory problems and cold infections. This review reports on the most highlighted polyphenolic compounds present in up to date literature and their specific antiviral perceptive properties that might enhance the body immunity facing COVID-19, and other viral infectious diseases. In fact, several studies and clinical trials increasingly proved the role of polyphenols in controlling numerous human pathogens including SARS and MERS, which are quite similar to COVID-19 through the enhancement of host immune response against viral infections by different biological mechanisms. Thus, polyphenols ought to be considered as a potential and valuable source for designing new drugs that could be used effectively in the combat against COVID‐19 and other rigorous diseases.

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Section: Quercetinmentioning

confidence: 99%

The upshot of Polyphenolic compounds on immunity amid COVID-19 pandemic and other emerging communicable diseases: An appraisal

Khalil

Tazeddinova

2020

Nat. Prod. Bioprospect.

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“…Antiviral effect of the A. pavonina seed and fruits aqueous extracts were conducted by Chiang et al (2003). The extracts were tested against adenoviruses (ADV) and herpes simplex viruses (HSV).…”

Section: Antiviral Activitymentioning

confidence: 99%

Advances in the research of Adenanthera pavonina: From traditional use to intellectual property

GeronÃ§o¹,

Melo²,

Barros³

et al. 2020

J. Med. Plants Res.

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Adenanthera pavonina, an Asian native leguminous, is a well known highly used plant in traditional medicine. Such broad herbal medicine applications motivated several researchers to study its chemical composition, mainly of its leaves, seeds, and barks, besides the pharmacological effects aiming to demonstrate scientific evidence of its empirical uses. Most studies have been conducted with plant derivatives, and more recent studies have focused on isolated compounds. The phytochemical screening revealed various secondary metabolites with diverse biological effects, including flavonoids, alkaloids, saponins, tannins, steroids, triterpenoids, polyphenols, anthraquinones, coumarins, glycosides and polysaccharides. Experimental studies of this plant have shown numerous pharmacological activities such as antidiarrheal, anti-inflammatory, antinociceptive, antioxidant, antimicrobial, anticancer, and others. Advances in the studies of phytochemistry and biological activity on this plant species over the last years led to the increasing interest of researchers in the protection of inventions focusing on its cosmetic, pharmaceutical and food applicability. This review summarizes the tremendous therapeutic and technological potential of A. pavonina that should be explored, opening new perspectives for future researches and the development of new products.

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“… Sapindaceae Seed [80] Glucose/mannose HSV-1 [81] Mangifera indica L. Anacardiaceae Fruit seed [82] Non-specified HSV, influenza virus [83] , [84] Momordica charantia L Cucurbitaceae Seed [85] Galactose/ N-Acetylgalactosamine HIV, HSV-1, H1N1, H3N2, H5N1 [86] , [87] , [88] Mucuna pruriens (L.) DC. Fabaceae Seed [89] Mannose HCV [90] Musa paradisiaca L. Musaceae Ripe fruit pulp [91] Mannose HSV-1, HSV-2 [91] Oryza sativa L. Poaceae – [82] N-Acetylglucosamine CMV, HSV [92] , [93] Phaseolus vulgaris L. Fabaceae Seed [94] , [95] Galactose HIV-1 RT [94] , [95] Psidium guajava L. Myrtaceae Fruit [96] Galactose H1N1 [97] Pisum sativum L. Fabaceae Seed [82] , [98] Mannose/galatose HCV, ADV [98] , …”

Section: Introductionmentioning

confidence: 99%

Plant lectins as prospective antiviral biomolecules in the search for COVID-19 eradication strategies

Ahmed

Jahan

Nissapatorn

et al. 2022

Biomedicine & Pharmacotherapy

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Lectins or clusters of carbohydrate-binding proteins of non-immune origin are distributed chiefly in the Plantae. Lectins have potent anti-infectivity properties for several RNA viruses including SARS-CoV-2. The primary purpose of this review is to review the ability of lectins mediated potential biotherapeutic and bioprophylactic strategy against coronavirus causing COVID-19. Lectins have binding affinity to the glycans of SARS-COV-2 Spike glycoprotein that has N-glycosylation sites. Apart from this, the complement lectin pathway is a “first line host defense” against the viral infection that is activated by mannose-binding lectins. Mannose-binding lectins deficiency in serum influences innate immunity of the host and facilitates infectious diseases including COVID-19. Our accumulated evidence obtained from scientific databases particularly PubMed and Google Scholar databases indicate that mannose-specific/mannose-binding lectins (MBL) have potent efficacies like anti-infectivity, complement cascade induction, immunoadjuvants, DC-SIGN antagonists, or glycomimetic approach, which can prove useful in the strategy of COVID-19 combat along with the glycobiological aspects of SARS-CoV-2 infections and antiviral immunity. For example, plant-derived mannose-specific lectins BanLac, FRIL, Lentil, and GRFT from red algae can inhibit and neutralize SARS-CoV-2 infectivity, as confirmed with in-vitro , in-vivo , and in-silico assessments. Furthermore, Bangladesh has a noteworthy resource of antiviral medicinal plants as well as plant lectins. Intensifying research on the antiviral plant lectins, adopting a glyco-biotechnological approach, and with deeper insights into the “glycovirological” aspects may result in the designing of alternative and potent blueprints against the 21st century's biological pandemic of SARS-CoV-2 causing COVID-19

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Antiviral Activity of Eight Commonly Used Medicinal Plants in Taiwan

Cited by 13 publications

References 20 publications

The upshot of Polyphenolic compounds on immunity amid COVID-19 pandemic and other emerging communicable diseases: An appraisal

The upshot of Polyphenolic compounds on immunity amid COVID-19 pandemic and other emerging communicable diseases: An appraisal

Advances in the research of Adenanthera pavonina: From traditional use to intellectual property

Plant lectins as prospective antiviral biomolecules in the search for COVID-19 eradication strategies

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