Infectious Disease Clinics of North America volume 19, issue 3, P713-729 2005 DOI: 10.1016/j.idc.2005.05.006 View full text
Ethan G. Leonard, Grace A. McComsey

Abstract: Although highly active antiretroviral therapy (HAART) has positively altered the morality rates in HIV-infected children, these drugs have the potential to cause significant morbidity. These drugs cause changes in fat distribution, lipid profiles, glucose, homeostasis, and bone turnover. The direct relationship between duration of drug exposure and increased risk of cardiovascular disease is particularly concerning for HIV-infected infants and children, who likely will have longer cumulative exposure to HAART.…

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