2001
DOI: 10.1179/135100001101536391
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Abstract: We investigated the antioxidant activity of phenylpropionic acids--caffeic (CAF), ferulic (FER), para-coumaric (COU) and cinnamic (CIN)--and phenolic acids and related compounds--gallic (GAL), methyl gallate (meGAL), vanillic (VAN) and gentisic (GEN)--using visible spectroscopy, inhibition of nitroblue tetrazolium (NBT) reduction, and electrochemical methods including cyclic voltammetry and potentiometry. In the spectroscopic assays, only CAF, GAL and meGAL were able to inhibit NBT reduction. The same compound… Show more

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Cited by 116 publications
(88 citation statements)
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“…AAPH: 2,2'-azobis(2-amidinopropane) dihydrochloride; ABTS •+ : 2,2'-azinobis- (3-ethylbenzthiazoline-6- O activity of different molecules [146]. Studies performed by our group and others on synthesized and natural HCAs have demonstrated that redox potential is closely related with the in vitro antioxidant activity of HCAs [82,135].…”
Section: [183] Cape and 5 Of Its Derivativesmentioning
confidence: 99%
“…AAPH: 2,2'-azobis(2-amidinopropane) dihydrochloride; ABTS •+ : 2,2'-azinobis- (3-ethylbenzthiazoline-6- O activity of different molecules [146]. Studies performed by our group and others on synthesized and natural HCAs have demonstrated that redox potential is closely related with the in vitro antioxidant activity of HCAs [82,135].…”
Section: [183] Cape and 5 Of Its Derivativesmentioning
confidence: 99%
“…meGAL is a phytochemical from various species including Meliaceae, Rosa Rugosa and Galla Rhois, and its derivative (-)-epigallocatechin gallate (EGCG) is a major pytochemical of green tea, well known antioxidative beverage (Chen and Zhang, 2003). The radical scavenging effect and inhibition of LPO have been reported as major activities of meGAL (Westenburg et al, 2000;Galato et al, 2001;Cho et al, 2003). In addition, meGAL possesses the biological activities including antiplatelet activity (Lim et al, 2004), protection of DNA damaging against oxidative stress (Hsieh et al, 2004), protection of lung injury induced by phosgene (Sciuto and Moran, 2001), attenuation of diabetic oxidative stress (Cho et al, 2004) and antiapoptotic activity (Sohi et al, 2003).…”
Section: Introductionmentioning
confidence: 99%
“…The persistent production of abnormally large amount of ROS or RNS, however, Methyl gallate and chemicals structurally related to methyl gallate protect human umbilical vein endothelial cells from oxidative stress may lead to persistent changes in signal transduction and gene expression, which in turn may give rise to certain diseases. meGAL is known as one of major antioxidants (Westenburg et al, 2000;Galato et al, 2001;Cho et al, 2003;Sohi et al, 2003). meGAL is a phytochemical from various species including Meliaceae, Rosa Rugosa and Galla Rhois, and its derivative (-)-epigallocatechin gallate (EGCG) is a major pytochemical of green tea, well known antioxidative beverage (Chen and Zhang, 2003).…”
Section: Introductionmentioning
confidence: 99%
“…It was illustrated, that; the antioxidant property of phenolic compounds increases within the increasing in the number of hydroxyl groups connected to the aromatic ring as well as steric freedom [54,55]. Clearly, the para-substituted hydroxyl group was observed to be highly proficient in radical scavenging activity.…”
Section: General Sign and Behavioral Analysismentioning
confidence: 93%