Antimicrobial susceptibility pattern of Stenotrophomonas species isolated from Mexico

Abstract

Background: Stenotrophomonas species are multi-resistant bacteria with ability to cause opportunistic infections.
 Objective: We isolated 45 Stenotrophomonas species from soil, sewage and the clinic with the aim of investigating their susceptibility to commonly used antimicrobial agents.
 Methodology: The identities of isolates were confirmed with 16S rRNA gene sequence and MALDI-TOF analysis. Anti-mi- crobial resistance, biofilm production and clonal diversity were also evaluated. The minimum inhibitory concentration technique as described by Clinical & Laboratory Standards Institute: CLSI Guidelines (CLSI) was employed for the evaluation of isolate susceptibility to antibiotics.
 Result: Forty-five Stenotrophomonas species which include 36 environmental strains and 9 clinical strains of S. maltophilia were considered in this study. 32 (88.9 %) environmental strains were identified to be S. maltophilia, 2 (5.6 %) were Stenotrophomonas nitritireducens, and 2 (5.6 %) cluster as Stenotrophomonas spp. Stenotrophomonas isolates were resistant to at least six of the antibiotics tested, including Trimethoprim/Sulfamethoxazole (SXT).
 Conclusion: Environmental isolates from this study were resistant to SXT which is commonly used for the treatment of S. maltophilia infections. This informs the need for good public hygiene as the environment could be a reservoir of multi-resistant bacteria. It also buttresses the importance of surveillance study in the management of bacterial resistance.
 Keywords: Stenotrophomonas; environmental; biochemical characterization; clonal diversity; anti-microbial susceptibility.

Comparative Study on Jejunal Immunity and Microbial Composition of Growing-Period Tibetan Pigs and Duroc × (Landrace × Yorkshire) Pigs

“…In addition, Lactobacillus are reported as probiotics in virtue of their anti-inflammatory ability ( 25 ), presence of three species of Solibacillus have been reported, of which Solibacillus silvestris can produce antineoplastic biomolecule ( 26 ). On the other hand, Stenotrophomonas species are multi-resistant bacteria with ability to cause opportunistic infections ( 27 ), and Pseudomonas has been reported as a known pathogen of mastitis microbiota in ruminants ( 28 ). Consequently, the intestinal microflora of TP pigs are more probably “healthier” than DLY pigs.…”

Emerging infections in vulnerable hosts: Stenotrophomonas maltophilia and Elizabethkingia anophelis

“…The rates of susceptibility of S. maltophilia to antimicrobial agents reported during 2020–2022 are listed in Table 2[28–30,39,49,95–120]. TMP-SMZ is the current treatment of choice for S. maltophilia infections because of its good in vitro susceptibility rates and extensive use in clinical settings.…”

Metagenome-Assembled Genome Sequence of Stenotrophomonas maltophilia Strain UJ_SKK_5.5, Obtained from the Gut Microbiome of a Macrotermes bellicosus Termite Collected from Hot, Arid Nigeria

“…Stenotrophomonas species occur ubiquitously ( 1 ). They have biotechnological potentials including producing antimicrobial compounds, generating plant growth factors, bioremediation and phytoremediation ( 2 – 4 ), lignocellulose degradation ( 5 ), high resistance to heavy metals and antibiotics ( 6 ), and roles in nitrogen and sulfur cycles ( 1 ). Stenotrophomonas maltophilia is an emerging human pathogen ( 6 ).…”

“…They have biotechnological potentials including producing antimicrobial compounds, generating plant growth factors, bioremediation and phytoremediation ( 2 – 4 ), lignocellulose degradation ( 5 ), high resistance to heavy metals and antibiotics ( 6 ), and roles in nitrogen and sulfur cycles ( 1 ). Stenotrophomonas maltophilia is an emerging human pathogen ( 6 ). Here, we report the genome sequence of Stenotrophomonas maltophilia strain UJ_SKK_5.5 derived from the gut of a Macrotermes bellicosus termite.…”