Antimicrobial Susceptibility of Clinically Significant Isolates of Enterobacter Spp., Obtained From Patients, Hospitalised in Varna University Hospital During the Period 2014 – 2016

Dimitrova, Dobromira; Stoeva, Temenuga; Markovska, Rumyana; Stankova, Petya; Bozhkova, Milena; Nedelcheva, Gergana; Mitov, Ivan

doi:10.5272/jimab.2017234.1828

JofIMAB

2017

DOI: 10.5272/jimab.2017234.1828

|View full text |Cite

Antimicrobial Susceptibility of Clinically Significant Isolates of Enterobacter Spp., Obtained From Patients, Hospitalised in Varna University Hospital During the Period 2014 – 2016

Dobromira Dimitrova¹,

Temenuga Stoeva²,

Rumyana Markovska³

et al.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2018

Publication Types

Select...

Article1

Relationship

Self Cite0

Independent1

Authors

Journals

Cited by 1 publication

(1 citation statement)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…28 Interestingly, Enterobacter isolates were highly sensitive to chloramphenicol (84%), a result similar to that obtained in India 29 .The higher levels of resistance to these antimicrobials is probably associated with possible production of plasmid-mediated ESBLs. Some of these plasmids in Enterobacter isolates may also carry genes that encode resistance to trimethoprime/sulfamethoxazole, quinolones and aminoglycosides 30 .…”

mentioning

confidence: 99%

FimH Adhesin among Enterobacter spp. Isolates and its Relation to Biofilm Formation and Antimicrobial Resistance Pattern

Ghonaim

Elkhyat

El-Hefnawy

et al. 2018

Egyptian Journal of Medical Microbiology

View full text Add to dashboard Cite

Background: Enterobacter spp., which are able to carry a number of antibioticresistance genes, can cause a variety of infections especially in immune-compromised individuals and patients from intensive care units (ICUs). Objectives: To assess the prevalence of Enterobacter spp. in Menoufia University Hospitals, and to investigate the relation between antimicrobial susceptibility patterns and biofilm production. Methodology: A total 296 clinical samples from patients admitted to Menoufia University Hospitals. Enterobacter spp. were identified by standard microbiological methods and Vitek-2 system. All Enterobacter isolates antibiogram was tested by the modified Kirby Bauer disk diffusion method, and for extended-spectrum β-lactamases and metallo-β-lactamase production. Biofilm production was detected by congo red agar, modified congo red agar methods and PCR. Results: Enterobacter spp. represented 17.3% of all the collected nosocomial isolates. Vitek-2 system showed that the predominant spp. was Enterobacter aerogenes (44%). Enterobacter isolates were resistant to amoxicillin (100%), doxycycline (82%) and gentamycin (76%). The rates of resistance to ceftriaxone, cefoxitin, cefepime, and amikacin were 64%, 72%, 60% and 70% respectively. Half of Enterobacter isolates were sensitive to piperacillin/tazobactam, meropenem, ciprofloxacin, ofloxacin and norfloxacin while 84% were sensitive to chloramphenicol. Production of ESβLs and MβL was found among 28% and 22% of isolates respectively. Biofilm production was found among 50% by CRA method and 56% by MCRA method, while conventional PCR showed fimH gene among 58% of Enterobacter isolates. Conclusion: Enterobacter spp. are serious nosocomial pathogens as they can produce ESβLs and carbapenemase, and produce biofilm that is related to their antimicrobial resistance. Therefore, their adequate prevention and control is imperative.

show abstract

mentioning

confidence: 99%

FimH Adhesin among Enterobacter spp. Isolates and its Relation to Biofilm Formation and Antimicrobial Resistance Pattern

Ghonaim

Elkhyat

El-Hefnawy

et al. 2018

Egyptian Journal of Medical Microbiology

View full text Add to dashboard Cite

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

hi@scite.ai

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Antimicrobial Susceptibility of Clinically Significant Isolates of Enterobacter Spp., Obtained From Patients, Hospitalised in Varna University Hospital During the Period 2014 – 2016

Cited by 1 publication

References 0 publications

FimH Adhesin among Enterobacter spp. Isolates and its Relation to Biofilm Formation and Antimicrobial Resistance Pattern

FimH Adhesin among Enterobacter spp. Isolates and its Relation to Biofilm Formation and Antimicrobial Resistance Pattern

Contact Info

Product

Resources

About