DOI: 10.17265/2159-5828/2016.02.002
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Marcos Antonio Neves, Porsry Ung, Kunihiko Uemura, Chieko Takahashi, Isao Kobayashi, Patrizia Romano, Mitsutoshi Nakajima

Abstract: Abstract:The aim of this study was to elucidate the mode of action of two antimicrobial compounds, nisin, which is hydrophilic, and the lipophilic compound carvacrol. For that purpose, both antimicrobials were loaded into Oil-in-/Water nanoemulsions, and their antimicrobial activity against Bacillus subtilis was investigated. The experimental results indicated that the O/W nanoemulsions loaded with both, nisin and carvacrol, having Sauter mean diameter (d 3,2 ) of around 120 nm, were considerably stable under…

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