Antimicrobial effect of Helichrysum plicatum DC. subsp. plicatum extracts on Escherichia coli O157:H7

Aslan, Mustafa; Demir, Aysel Elik; Mercanoglu, B.; Aykac, A.; Yeşilada, Erdem

doi:10.1055/s-2007-986990

Cited by 2 publications

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“…Helichrysum stoechas subsp. barrelieri (Ten) is a sub-taxon of H. stoechas that grows in the southern Marmara, Aegean, and Mediterranean regions of Türkiye as well as Albania, Cyprus, Egypt, Greece, and Italy (Aksoy et al, 2011;Aslan, 1994;Eroğlu, 2018). The ethnopharmacological records of H. stoechas indicate that the plant's capitulum is used for its diuretic, emmenagogue, anticoagulant, kidney stone-lowering, appetite-raising, and anthelmintic properties along with its utilization in the treatment of dermatological illnesses such as dermatitis, burn-wound treatment, and body crack healing (Gras et Alzheimer's disease (AD) is an incurable and progressive neurological disease that deprives people of their memory and cognitive abilities, primarily affecting the elderly population.…”

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confidence: 99%

Enzyme inhibitory and antioxidant activities and HPLC quantification of chlorogenic acid in Helichrysum stoechas (L.) Moench and H. stoechas subsp. barrelieri (Ten) Nyman

Abacı

Gök

Aslan

et al. 2023

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The inhibitory effects of ethanol (80%) and aqueous extracts of Helichrysum stoechas (L.) Moench and H. stoechas subsp. barrelieri (Ten) Nyman on acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), two sister enzymes associated with pathogenesis of Alzheimer's disease (AD), as well as on elastase and collagenase, linked to inflammation and skin aging, were investigated. Simultaneously, antioxidant activity of the extracts was assessed through DPPH radical scavenging activity, ferric reducing antioxidant power (FRAP), and metal-chelating activity assays, since oxidative damage plays a critical role in both AD pathophysiology and skin aging. Total phenol and flavonoid contents in the extracts were spectrophotometrically determined. The highest AChE inhibitory activity (44.60 ± 4.4% at 2000 µg/mL) was found in the ethanol extract of H. stoechas subsp. barrelieri collected from Hatay, and the uppermost BChE inhibitory activity at same concentration was found in the aqueous extract of H. stoechas subsp. barrelieri collected from Izmir (80.24 ± 2.63%, IC50: 38.52 ± 1.41 µg/mL). Both of them inhibited AChE and BChE in a concentration-dependent manner. Nevertheless, none of the extracts from the two plants inhibited the elastase and collagenase. Although both ethanolic and aqueous extracts had significant antioxidant activity in DPPH radical scavenging and FRAP assays, they demonstrated inadequate antioxidant activity in metal-chelating assay. Chlorogenic acid was quantified in the extracts using HPLC. The mentioned two extracts having strong cholinesterase (ChE) inhibition had also the highest chlorogenic acid content. The ethanol extract of H. stoechas (Hatay sample) and the aqueous extract of H. stoechas (Izmir sample) seem to contain promising ChE inhibitors, which deserve further investigation.

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Section: Introductionmentioning

confidence: 99%

Enzyme inhibitory and antioxidant activities and HPLC quantification of chlorogenic acid in Helichrysum stoechas (L.) Moench and H. stoechas subsp. barrelieri (Ten) Nyman

Abacı

Gök

Aslan

et al. 2023

CUPMAP

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“…plicatum are fl avonoids (ÇUBUKÇU and MERIÇLI 1977) and essential oils (SEZIK and ASLAN 2000). This taxon is responsible for the remarkable lesion therapeutic (SEZIK and ASLAN 2000), antibacterial (ERDOĞRUL, ÇAKIROĞLU and KARAMAN 2001;ASLAN et. al.…”

Section: Introductionmentioning

confidence: 99%

The Genotoxic and Antimitotic Properties of Helichrysum plicatum Herbal Teas Widely Consumed in Turkey

et al. 2010

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-Helichrysum plicatum DC. subsp. plicatum (Asteraceae), (common name; everlasting) is a medicinal plant and natural product. For centuries, it has been used as tea in Turkey because of its medicinal properties. There are few reports in literature about genotoxic effects of this plant. The aim of this work is to evaluate the genotoxic and antimitotic effects on human lymphocyte cultures induced by aqueous (decoction) extracts of this plant which were assayed in different concentrations (0.01, 0.05, 0.1, 0.5 and 1 mg/mL). Helichrysum plicatum subsp. plicatum extracts used in alternative medicine induced the formation of micronuclei, decreased the mitotic and replication indexes compared to untreated group (control). Indeed, it causes chromosomal damage (an increase in micronucleus) and delay in the cell division (decrease in mitotic and replication indexes). It should therefore not be used freely in high concentrations in alternative medicine although its antiproliferative activity may suggest as an antimitotic product.

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Antimicrobial effect of Helichrysum plicatum DC. subsp. plicatum extracts on Escherichia coli O157:H7

Cited by 2 publications

References 0 publications

Enzyme inhibitory and antioxidant activities and HPLC quantification of chlorogenic acid in Helichrysum stoechas (L.) Moench and H. stoechas subsp. barrelieri (Ten) Nyman

Enzyme inhibitory and antioxidant activities and HPLC quantification of chlorogenic acid in Helichrysum stoechas (L.) Moench and H. stoechas subsp. barrelieri (Ten) Nyman

The Genotoxic and Antimitotic Properties of Helichrysum plicatum Herbal Teas Widely Consumed in Turkey

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