Antimicrobial constituents of the leaves of Acalypha wilkesiana and Acalypha hispida

Abstract

An activity directed fractionation of a 50% aqueous ethanol extract of A. wilkesiana and A. hispida leaves resulted in the isolation of gallic acid, corilagin and geraniin as the compounds responsible for the observed antimicrobial activity. Quercetin 3-O-rutinoside and kaempferol 3-O-rutinoside were also isolated from the inactive fraction of A. hispida. The structures were established by permethylation, 2D - NMR ((1)H and (13)C) and MS data.

Antibacterial and antifungal screening of extracts from six medicinal plants collected in Kinshasa-Democratic Republic of Congo against clinical isolate pathogens

“…Our results are only qualitatively in good agreement with those previsously reported by Kambu et al (1990) and Tona et al (1999) concerning the antibacterial activity of P. macrophylla stem bark, the antibacterial and antifungal activity of A. conyzoides leaves described by Ahmagboul et al,(1985), Yamamoto et al, (1991), Gamesan and Krishnaraju (1995), Dayie et al, (2008) and Okwori et al (2013) and the antibacterial and antifungal activity of A. wilkesiana leaves reported by Alade and Irobi (1993); Adesina et al, (2000); Gotep et al, (2010) and Haruna et al (2013). Although these activities were carried out by the diffusion method.…”

Antibacterial and antifungal screening of extracts from six medicinal plants collected in Kinshasa-Democratic Republic of Congo against clinical isolate pathogens

“…Our results are only qualitatively in good agreement with those previsously reported by Kambu et al (1990) and Tona et al (1999) concerning the antibacterial activity of P. macrophylla stem bark, the antibacterial and antifungal activity of A. conyzoides leaves described by Ahmagboul et al,(1985), Yamamoto et al, (1991), Gamesan and Krishnaraju (1995), Dayie et al, (2008) and Okwori et al (2013) and the antibacterial and antifungal activity of A. wilkesiana leaves reported by Alade and Irobi (1993); Adesina et al, (2000); Gotep et al, (2010) and Haruna et al (2013). Although these activities were carried out by the diffusion method.…”

Nitric Oxide Radical Scavenging Active Components From Phyllanthus emblica L.

“…All of the compounds are found to be TLC/HPLC pure. The structures of the isolated compounds were determined on the basis of their Mass, 1 H and 13 C NMR spectral data, and confirmed by comparison with literature data [14][15][16][17].…”

Antimicrobial and Antioxidant Activity of Emblica Extracts Obtained by Supercritical Carbon Dioxide Extraction and Methanol Extraction

“…Greenish yellow crystalline powder; UV λ max (CH 3 OH) nm: 218, 274; FAB‐MS, m/z 953 [M + H] + , and 975 [M + Na] + ; 13 CNMR (CD 3 COCD 3 ): δ63.0, 64.6, 66.5, 70.3, 73.6, 91.7, 92.6, 96.3, 108.4, 110.6, 111.0, 114.1, 116.2, 117.6, 120.2, 124.4, 125.5, 137.6, 138.7, 140.8, 145.3, 145.5, 166.0, 166.4, 167.5, 169.9, and 195.1. The data are in agreement with the reported literature values (Adesina et al. 2000).…”

Antibacterial and antifungal screening of extracts from six medicinal plants collected in Kinshasa-Democratic Republic of Congo against clinical isolate pathogens

“…Our results are only qualitatively in good agreement with those previsously reported by Kambu et al (1990) and Tona et al (1999) concerning the antibacterial activity of P. macrophylla stem bark, the antibacterial and antifungal activity of A. conyzoides leaves described by Ahmagboul et al,(1985), Yamamoto et al, (1991), Gamesan and Krishnaraju (1995), Dayie et al, (2008) and Okwori et al (2013) and the antibacterial and antifungal activity of A. wilkesiana leaves reported by Alade and Irobi (1993); Adesina et al, (2000); Gotep et al, (2010) and Haruna et al (2013). Although these activities were carried out by the diffusion method.…”

Nitric Oxide Radical Scavenging Active Components From Phyllanthus emblica L.

“…All of the compounds are found to be TLC/HPLC pure. The structures of the isolated compounds were determined on the basis of their Mass, 1 H and 13 C NMR spectral data, and confirmed by comparison with literature data [14][15][16][17].…”

Antimicrobial and Antioxidant Activity of Emblica Extracts Obtained by Supercritical Carbon Dioxide Extraction and Methanol Extraction

“…Greenish yellow crystalline powder; UV λ max (CH 3 OH) nm: 218, 274; FAB‐MS, m/z 953 [M + H] + , and 975 [M + Na] + ; 13 CNMR (CD 3 COCD 3 ): δ63.0, 64.6, 66.5, 70.3, 73.6, 91.7, 92.6, 96.3, 108.4, 110.6, 111.0, 114.1, 116.2, 117.6, 120.2, 124.4, 125.5, 137.6, 138.7, 140.8, 145.3, 145.5, 166.0, 166.4, 167.5, 169.9, and 195.1. The data are in agreement with the reported literature values (Adesina et al. 2000).…”

Antibacterial and antifungal screening of extracts from six medicinal plants collected in Kinshasa-Democratic Republic of Congo against clinical isolate pathogens

“…Our results are only qualitatively in good agreement with those previsously reported by Kambu et al (1990) and Tona et al (1999) concerning the antibacterial activity of P. macrophylla stem bark, the antibacterial and antifungal activity of A. conyzoides leaves described by Ahmagboul et al,(1985), Yamamoto et al, (1991), Gamesan and Krishnaraju (1995), Dayie et al, (2008) and Okwori et al (2013) and the antibacterial and antifungal activity of A. wilkesiana leaves reported by Alade and Irobi (1993); Adesina et al, (2000); Gotep et al, (2010) and Haruna et al (2013). Although these activities were carried out by the diffusion method.…”

Nitric Oxide Radical Scavenging Active Components From Phyllanthus emblica L.

“…All of the compounds are found to be TLC/HPLC pure. The structures of the isolated compounds were determined on the basis of their Mass, 1 H and 13 C NMR spectral data, and confirmed by comparison with literature data [14][15][16][17].…”

Antimicrobial and Antioxidant Activity of Emblica Extracts Obtained by Supercritical Carbon Dioxide Extraction and Methanol Extraction

“…Greenish yellow crystalline powder; UV λ max (CH 3 OH) nm: 218, 274; FAB‐MS, m/z 953 [M + H] + , and 975 [M + Na] + ; 13 CNMR (CD 3 COCD 3 ): δ63.0, 64.6, 66.5, 70.3, 73.6, 91.7, 92.6, 96.3, 108.4, 110.6, 111.0, 114.1, 116.2, 117.6, 120.2, 124.4, 125.5, 137.6, 138.7, 140.8, 145.3, 145.5, 166.0, 166.4, 167.5, 169.9, and 195.1. The data are in agreement with the reported literature values (Adesina et al. 2000).…”