Antimicrobial Agents in Films and Coatings

Premjit, Yashaswini; Malik, Gulshan Kumar

doi:10.1002/9781119702313.ch9

Cited by 3 publications

(3 citation statements)

References 170 publications

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“…To provide an antimicrobial environment, εpolylysine (ε-PL) was selected. ε-PL is a polypeptide polymer that consists of 25-30 lysine residues and demonstrates a wide range of antibacterial properties by employing various mechanisms such as membrane disruption, respiration inhibition, and enzymatic and protein synthesis interference [5,6]. Apart from its antibacterial activity, ε-PL also exhibits excellent biocompatibility and biodegradability, making it a sought-after material in the field of biomedical research [7,8].…”

Section: Introductionmentioning

confidence: 99%

Antibacterial, ROS scavenging and angiogenesis promoting ϵ-Polylysine/gelatin based hydrogel containing CTLP to regulate macrophages for pressure ulcer healing

Lin,

Tang,

Zhong

et al. 2024

Biofabrication

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Pressure ulcers have emerged as a substantial burden on individuals and society. The introduction of innovative dressings that facilitate the healing of pressure ulcer wounds represents a cost-effective alternative for treatment. In this study, we focus on the preparation of Carthamus tinctorius L. polysaccharide (CTLP) as hydrogel microspheres, which are then encapsulated within a hydrogel matrix crosslinked with phenylboronic acid gelatin (Gelatin-PBA) and ε-polylysine-grafted catechol (ε-PL-Cat) to enable sustained release for promoting pressure ulcer healing. The presented GPL/CTLP-MPs hydrogel demonstrated outstanding self-healing properties. In addition, in vitro experiments revealed that the hydrogel exhibited remarkable antibacterial activity, excellent biocompatibility. And it showed the capacity to promote vascular formation, effectively scavenge reactive oxygen species (ROS), and facilitate macrophage polarization from the M1 to M2 phenotype. In vivo wound healing of mice pressure ulcers indicated that the prepared GPL/CTLP-MPs hydrogel effectively accelerated the formation of granulation tissue and facilitated the healing of the wounds. In summary, in vivo and in vitro experiments consistently highlight the therapeutic potential of GPL/CTLP-MPs hydrogel in facilitating the healing process of pressure ulcers.

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Section: Introductionmentioning

confidence: 99%

Antibacterial, ROS scavenging and angiogenesis promoting ϵ-Polylysine/gelatin based hydrogel containing CTLP to regulate macrophages for pressure ulcer healing

Lin,

Tang,

Zhong

et al. 2024

Biofabrication

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“…Using biopolymers in packaging films and coatings with added antibacterial compounds is an innovative solution. Biopolymer‐based packaging acts as a carrier for active ingredients that act against microorganisms present in food, preventing spoilage and thus extending the shelf life of food (Premjit et al., 2022). Over the past decade, using antibacterial components such as organic acids, essential oils, bacteriocins, and enzymes in biopolymers has been extensively studied (Bangar et al., 2021; Premjit et al., 2022).…”

Section: Introductionmentioning

confidence: 99%

“…Biopolymer‐based packaging acts as a carrier for active ingredients that act against microorganisms present in food, preventing spoilage and thus extending the shelf life of food (Premjit et al., 2022). Over the past decade, using antibacterial components such as organic acids, essential oils, bacteriocins, and enzymes in biopolymers has been extensively studied (Bangar et al., 2021; Premjit et al., 2022). However, their application in food is limited as they may interfere with food organoleptic properties and are sometimes harmful at high levels (Atarés & Chiralt, 2016; Santos et al., 2022).…”

Section: Introductionmentioning

confidence: 99%

Application of bacteriophages in biopolymer‐based functional food packaging films

Rindhe,

Khan,

Priyadarshi

et al. 2024

Comp Rev Food Sci Food Safe

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Recently, food spoilage caused by pathogens has been increasing. Therefore, applying control strategies is essential. Bacteriophages can potentially reduce this problem due to their host specificity, ability to inhibit bacterial growth, and extend the shelf life of food. When bacteriophages are applied directly to food, their antibacterial activity is lost. In this regard, bacteriophage‐loaded biopolymers offer an excellent option to improve food safety by extending their shelf life. Applying bacteriophages in food preservation requires comprehensive and structured information on their isolation, culturing, storage, and encapsulation in biopolymers for active food packaging applications. This review focuses on using bacteriophages in food packaging and preservation. It discusses the methods for phage application on food, their use for polymer formulation and functionalization, and their effect in enhancing food matrix properties to obtain maximum antibacterial activity in food model systems.

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