Antimicrobial Activity of Aqueous Extracts of Different Parts of Terminalia catappa L.

Venkatalakshmi, P.; Brindha, P.

doi:10.20546/ijcmas.2016.512.053

Cited by 7 publications

(8 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Globally, fruit nutriments have beneficial health therapeutic and economic benefits (Venkatalakshmi and Brindha 2016). Indian almond seed, Terminalia catappaLinn (family Combretaceae) is a plant species with good records of medicinal importance associated with its chemical constituents.…”

Section: Introductionmentioning

confidence: 99%

Further studies on evaluation of the toxicity potential of Terminalia catappa Lin. Combretaceae leaf extract: effects on thehistology, liver enzymes, and haematology profile of albino rats

2021

JJBS

View full text Add to dashboard Cite

There is a global utilization of Terminalia catappa as a medicinal plant. In this study, the effect of aqueous leaf extract of Terminalia catappa (ALETA) on the haematological profile, liver function enzymes, and histology of some organs in albino rats was examined. Seventy-two healthy albino rats were randomly distributed into four groups (A-D) in 6 rats per triplicate. The normal control received 1ml/kg of deionized water while groups B-D received 150, 300, and 450 mg/kg ALETA, respectively for 21 days. Minor cytoplasm vacuolation, focal necrosis, and dilated sinusoids were observed in the liver tissue. The kidney showed minor degenerative changes characterized by few shrunk glomeruli while no tissue damage was observed in the heart tissue and minor passive congestion was observed in the pyloric stomach. The packed cell volume (PCV), red blood cell (RBC), haemoglobin (HB), neutrophils (N), eosinophils (E), monocytes (M), lymphocytes (L), and means cell haemoglobin (MCH) responded significantly (p<0.05) to treatment dosage. Meanwhile, the increased aspartate aminotransfarase (AST), alanine aminotransfarase (ALT), acid phosphatase (ACP) and alkaline phosphatase (ALP) were an indication of compromised liver function by the ALETA. There is a need for safety assessment, regulation, and intake of Terminalia catappa as a medicinal herb.

show abstract

Section: Introductionmentioning

confidence: 99%

Further studies on evaluation of the toxicity potential of Terminalia catappa Lin. Combretaceae leaf extract: effects on thehistology, liver enzymes, and haematology profile of albino rats

2021

JJBS

View full text Add to dashboard Cite

show abstract

“…The result indicated that, the plants studied possess antibacterial activity both on gram-negative and gram-positive bacterial isolates, which may be due to the presence of bioactive components. Several studies shown that T. catappa possess antifungal [85][86][87][88], antibacterial [86][87][88], antidiabetic, antiinflammatory, antioxidant, anti-HIV [86,89], antitumor [86], anticancer [89] as well as other pharmacological activities.…”

Section: Pharmacological Activities Of Nigerian Medicinal Plantsmentioning

confidence: 99%

Phytochemical Compositions in Some Nigerian Medicinal Plants and Their Pharmacological Properties: A Review

Kutama¹,

Abdulkadir²,

Kwalli³

et al. 2018

View full text Add to dashboard Cite

Nigeria is naturally blessed with both savannah and tropical rainforests vegetation and these offer a wide distribution of plants believed to possesses secondary metabolites which are responsible for treating or curing various diseases. Several researches have been carried out in order to explore and identify the chemical compositions responsible for various pharmacological activities in Nigerian medicinal plants. This paper discussed the meaning and historical development of medicinal plants. A brief account of phytochemicals (alkaloids and flavonoids) were also given. The plants presented in this paper confirmed the pharmacological activities of these plants and includes;

show abstract

“…Someone who has a low immune system will be very at risk for contracting this condition (Kalia et al, 2016) . Manusia memiliki sistem kekebalan di bawah sel fagositik yang menjadi pertahanan penting terhadap organisme dan sel ganas (Venkatalakshmi & Brindha, 2016). Activation of the immune system needs to be activated in order to play a role in fighting antigenic substances that enter the body.…”

Section: Introductionmentioning

confidence: 99%

“…Immunomodulatory drugs of synthetic origin have shown benefits, but they have also shown adverse side effects so that the use of such drugs has become less effective. Therefore, the development of research to find safer and more effective immunomodulators is very important (Venkatalakshmi & Brindha, 2016). Potential immunomodulatory agents to be developed from plant extracts, where these plant extracts generally have smaller side effects (Alamgir & Uddin, 2010).…”

Section: Introductionmentioning

confidence: 99%

Immunomodulator Effect of Cnidoscolus aconitifolius Leaves Extract on CD4+ and CD8+ Expression in Salmonella typhimurium infected mice

Hidayati,

Susanti,

Destiawan

et al. 2024

Pharmaciana

View full text Add to dashboard Cite

Typhoid fever is a common health problem in the community caused by Salmonella bacteria. The incidence rate of this infection will increase if a person's immune system is weakened. Plant extracts have been widely studied for their role in various pharmacological effects, including immunomodulatory effects. Among the plants with the potential to be used as an immunomodulatory substance is Cnidoscolus aconitifolius. Cnidoscolus aconitifolius leaves extract (CAE) contains flavonoids related to immunomodulatory activity. This study intends to ascertain how administering CAE affects the expression of CD4 + and CD8 + in Babl/c mice that have been infected with Salmonella typhimurium bacteria. The study was started by preparing 70% ethanol extract from Cnidoscolus aconitifolius leaves. Immunomodulatory activity testing was carried out preparing 30 Babl/C mice as experimental animals. Six mouse groups (the treatment group, the negative control, the positive control, and the healthy control) were allocated at random by giving CAE doses of 100 mg/kgBW, CAE doses of 200 mg/kgBW, and CAE doses of 400 mg/kgBW. Induction was carried out by oral infection with Salmonella thypimurium bacteria. After 3 days the infected mice were treated orally once a day for 7 days. Evaluation of CD4 + and CD8 + expression was carried out using the flow cytometry method of the lymph organs. The data was analyzed using the anova test and then the SPSS for Windows tool was used to do the post hoc test (Tukey). The results showed that giving CAE at doses of 100 mg/kgBW, CAE doses of 200 mg/kgBW and CAE doses of 400 mg/kgBW could increase the expression ratio of CD4 + and CD8 + . Conversely, administering 400 mg/kgBW of CAE produced noticeably different outcomes (p<0.05) from the negative control. This shows that the CAE has potential as an immunomodulatory agent that can improve immune function.

show abstract

Antimicrobial Activity of Aqueous Extracts of Different Parts of Terminalia catappa L.

Cited by 7 publications

References 8 publications

Further studies on evaluation of the toxicity potential of Terminalia catappa Lin. Combretaceae leaf extract: effects on thehistology, liver enzymes, and haematology profile of albino rats

Further studies on evaluation of the toxicity potential of Terminalia catappa Lin. Combretaceae leaf extract: effects on thehistology, liver enzymes, and haematology profile of albino rats

Phytochemical Compositions in Some Nigerian Medicinal Plants and Their Pharmacological Properties: A Review

Immunomodulator Effect of Cnidoscolus aconitifolius Leaves Extract on CD4+ and CD8+ Expression in Salmonella typhimurium infected mice

Contact Info

Product

Resources

About