volume 12, issue 4, P525-530 1978
DOI: 10.1002/jbm.820120407
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Abstract: Antiinflammatory activities of low- and high- molecular-weight polymers of o-methacryloyloxybenzoic acid were compared with the antiinflammatory activity of o-acetoxybenzoic (acetylsalicylic) acid in tests on hind-leg inflammations in rats induced by injection of either Freund's adjuvant or aqueous suspension of kaolin. The antiinflammatory activies of the orally administered polymers cooresponded to 40-90% of the activity of o-acetoxybenzoic acid, and were not substantially dependent on the degree of polymeri…

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