Antifungal activity of aqueous and methanolic extracts from the Mediterranean sea cucumber, Holothuria polii

The Biotechnological and Seafood Potential of <i>Stichopus regalis</i>

“…Also, saponins are highly revealed in the methanolic fraction since they are a polar solvent [11]. This antifungal activity can be associated to the presence of these saponins, which have been linked to the antifungal activity in other studies concerning Holothuria edulis and Stichopus chloronotus for Candida albicans [9], Psolus patagonicus for Cladosporium cladosporoides [24] and Holothuria polii for Aspergillus fumigatus and C. albicans [25]. Concerning C. albicans, the methanolic fraction showed the highest antifungal potential with IC 50 values being lowest than those reported by Hing et al (2007) [9] for H. edulis and S. chloronotus against C. albicans.…”

Antimicrobial Activity of Sea Cucumber (Stichopus variegatus) Body Wall Extract in Chabahar Bay, Oman Sea

“…Samples were washed with distilled water after being melted, and their internal organs were removed through an abdominal incision. The dried pieces of the body wall were extracted two times (15). The extraction process was implemented with the aim of separating the solved compounds in a solution or removing compounds from a solid mixture.…”

“…The small pieces of the body wall were kept in 300 mL each of aqueous methanol, methanol, chloroform, and n-hexane solutions for 72 hours. After filtering with filter paper, the resulting extracts were condensed under the condition of vacuum with a rotary machine at 40°C and were dried with a freeze drier (15,31).…”

“…This antimicrobial activity is attributed to triterpene glycosides (15), disulphate glycosides (16), steroid glycosides (17), polyhydroxy sterols (18), naphthoquinone pigments (19), lysozyme, and various precursors (20). Stichopus variegatus (also known as Stichopus hermanni) is a species that is most valued not only as a food source, but it also offers a variety of remedies which have been proven in an animal model system (21).…”

Antibacterial activity of the body wall extracts of sea cucumber (Invertebrata; Echinodermata) on infectious oral streptococci

“…Several studies have shown multiple biological activities of sea cucumber species. These include wound healing [5], antibacterial [6], antifungal [7], antiseptic [8] and antioxidant properties [9].…”