Anticariogenic potential of &lt;em&gt;Potentilla fulgens&lt;/em&gt; extract and its chemical constituents

Choudhary, Alka; Bihade, Umesh; Mittal, Amit Kumar; Chatterjee, Anupam; Banerjee, Uttam Chand; Singh, Inder Pal

doi:10.5138/09750185.1939

Cited by 6 publications

(5 citation statements)

References 21 publications

(22 reference statements)

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“…Epigallocatechin gallate was the most effective inhibitor against tested bacterial strains [16]. From Time-kill studies and biofilm formation inhibition assays, catechin (4α→8) epicatechin and Potentilla extracts could be employed as natural antibacterial agents in oral health care products [17].…”

Section: Anticariogenic Activitymentioning

confidence: 99%

“…Choudhary et al, [29] had undertaken extensive studies to evaluate the anticariogenic effects of the plant and search for potent anticariogenic phenolic molecules. Polyphenolic compounds-1.…”

Section: Phytochemical Constituentsmentioning

confidence: 99%

“…Epiafzelechin (4β→8) epicatechin 9.Catechin (4α→8) epicatechin 10. Afzelechin(4α→8)catechin and 11.Afzelechin (4α→8) epiafzelechin [29] were isolated from the roots of Potentilla fulgens using semi-preparative HPLC. The structure of the chemical compounds are given below.…”

Section: Phytochemical Constituentsmentioning

confidence: 99%

“…Fourteen marker compounds were detected in the crude methanol extract of P. fulgens by HPLC/UV methods at different wavelengths. Table 2 Quantization of isolated compounds in methanol extract and roots of P. fulgens Ursolic acid (0.82 ± 0.05%) and epicatechin (0.67 ± 0.03%) were the major compounds in the tested sample of roots [29]. In another study [30], from ethyl acetate extract of P. fulgens compounds, 2ɑ,3ɑ,20β-trihydroxyrus-13-en-28-oic acid, 2ɑ,3β,20βtrihydroxyurs-13en-28-oic, p-hydroxy benzaldehyde, gallic acid were isolated which exhibited good antioxidant activity.…”

Section: Phytochemical Constituentsmentioning

confidence: 99%

“…Epiafzelechin (4β→8) epicatechin 9.Catechin (4α→8) epicatechin 10. Afzelechin(4α→8)catechin and 11.Afzelechin (4α→8) epiafzelechin[29].…”

mentioning

confidence: 99%

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Potentilla fulgens: A Systematic Review on Traditional Uses, Pharmacology and Phytochemical Study with Reference to Anticancer Activity

Barua¹,

Yasmin²

2018

JNPR

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Potentilla fulgens has been extensively used in folk medicine by the local people of Meghalaya in North East India. Traditionally, the root-stock and the whole plant, Potentilla fulgens are utilized as astringent and tonic for curing the gums from tooth ailments. The aqueous root peel extract of this plant is consumed to get rid of intestinal infections and also the tap root is traditionally chewed along with betel nut (Areca catechu) and betel leaves (Piper betel) for various ailments. North East India has maximum incidence and occurrence of different types of oral cancer due to consumption of tobacco, tobacco related compounds and alcohol. Taking into consideration its high medicinal value and popularity of the plant, we have tried to compile and update the latest research work carried out by other workers and to explore its potential as anticancer therapy with a futuristic approach. Subsequently, the plant has been studied in detail on its various pharmacological activity by few researchers and two reviews were already published in the years 2009 and 2011, encompassing its pharmacological, taxonomical, phytochemical attributes. So, our aim was to explore the latest work done so far post 2011.

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Section: Anticariogenic Activitymentioning

confidence: 99%

Section: Phytochemical Constituentsmentioning

confidence: 99%

Section: Phytochemical Constituentsmentioning

confidence: 99%

Section: Phytochemical Constituentsmentioning

confidence: 99%

“…Epiafzelechin (4β→8) epicatechin 9.Catechin (4α→8) epicatechin 10. Afzelechin(4α→8)catechin and 11.Afzelechin (4α→8) epiafzelechin[29].…”

mentioning

confidence: 99%