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“…Alternatively, the epitopes recognized by the humoral response to the HSP-65 family during infection may be more specific than the results with cross-reactive monoclonals imply. This may be due to suppression of the response to broadly crossreacting epitopes (Cooper et al, 1984). Furthermore, the observation that a greater proportion of Brucella sera recognized the 62 kDa antigen provides some evidence for greater specificity.…”
Section: Discussionmentioning
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“…Alternatively, the epitopes recognized by the humoral response to the HSP-65 family during infection may be more specific than the results with cross-reactive monoclonals imply. This may be due to suppression of the response to broadly crossreacting epitopes (Cooper et al, 1984). Furthermore, the observation that a greater proportion of Brucella sera recognized the 62 kDa antigen provides some evidence for greater specificity.…”
Section: Discussionmentioning