Antibody-Functionalized Gold Nanoparticles as a Highly Sensitive Two-Step Colorimetric Biosensor for Detecting Salmonella Typhimurium in Food
Mario Anzevino,
Daniele Marra,
Andrea Fulgione
et al.
Abstract:The standard laboratory methods used to detect Salmonella are time-consuming, leading to unavoidable delays, which can be costly (e.g., food checks at customs) or even dangerous when quick alarms are needed (e.g., for potential outbreaks). To address this problem, we propose a rapid two-step colorimetric immunoassay. In the first step, gold nanoparticles interact with the sample, while in the second step, an optimized amount of saline solution is added to induce cluster formation among the unbound nanoparticle… Show more
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