volume 29, issue 2, P373-377 2012
DOI: 10.3233/jad-2011-111343
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Akio Kimura, Takeo Sakurai, Megumi Yamada, Akihiro Koumura, Yuichi Hayashi, Yuji Tanaka, Isao Hozumi, Hirofumi Ohtaki, Mitsuhiro Chousa, Masao Takemura, Mitsuru Seishima, Takashi Inuzuka

Abstract: Recent studies suggest that microvascular abnormalities are involved in pathology and progression of Alzheimer's disease. The purpose of this study was to examine the presence of antibodies against cerebral microvascular endothelial cells specific for Alzheimer's disease, and to evaluate the association of these antibodies with cognitive impairment. The study included patients with Alzheimer's disease (age ≥60 years; 24 patients), control subjects without neurological diseases (age ≥60 years; 19 subjects), pat…

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