Antibiotics for acute asthma

Abstract

Editorial group: Cochrane Airways Group. Publication status and date: Edited (no change to conclusions), published in Issue 1, 2009.

‘Evidence‐based implementation’ of paediatric asthma guidelines in a rural emergency department

“…There is also evidence 39 that patients want written instructions and advice for the first 24–48 h after an acute asthma attack, and a readily available pre‐formatted STAMP may have facilitated the increased compliance with this indicator. There is little role for antibiotic use in acute asthma, 40 and while antibiotic use dropped from 15% to 6% this did not reach statistical significance. The lack of statistical significance for this indicator may be due to the relatively low rates of prescribing, and hence good compliance to begin with.…”

‘Evidence‐based implementation’ of paediatric asthma guidelines in a rural emergency department

“…There is also evidence 39 that patients want written instructions and advice for the first 24–48 h after an acute asthma attack, and a readily available pre‐formatted STAMP may have facilitated the increased compliance with this indicator. There is little role for antibiotic use in acute asthma, 40 and while antibiotic use dropped from 15% to 6% this did not reach statistical significance. The lack of statistical significance for this indicator may be due to the relatively low rates of prescribing, and hence good compliance to begin with.…”

Management of severe asthma exacerbation: guidelines from the Société Française de Médecine d’Urgence, the Société de Réanimation de Langue Française and the French Group for Pediatric Intensive Care and Emergencies

“…An older placebo-controlled trial showed no symptomatic benefit of antibiotic therapy with amoxicillin in an adult population [59]. A meta-analysis including trials in children and adults was also negative [60]. In conclusion, there is no argument encouraging the routine administration of penicillin or of macrolides to adults with SAE requiring hospitalization.…”

An integrative review of systematic reviews related to the management of breathlessness in respiratory illnesses

“…Treatments included: anti-leukotrienes [ 64 , 65 ]; beta-agonists (inhaled/non-inhaled) [ 61 - 63 , 66 - 75 ]; allergen immunotherapy [ 76 ]; anti-IgE [ 77 ]; antibiotics [ 78 ]; anti-cholinergics [ 57 ]; azathioprine [ 79 ]; beclomethasone [ 80 - 82 ]; budesonide [ 83 , 84 ]; caffeine [ 85 ]; beta-blockers [ 58 ]; chloroquine [ 86 ]; corticosteroids (inhaled/non-inhaled) [ 59 , 60 , 87 - 91 ]; cyclosporine [ 92 ]; fluticasone [ 93 - 96 ]; anti-gastro-oesophageal reflux treatment [ 97 ]; gold [ 98 ]; inhaled/non-inhaled magnesium sulphate [ 98 , 100 ]; macrolides [ 101 , 102 ]; methotrexate [ 103 ]; oxatomide [ 104 ]; and tailored interventions based on sputum eosinophils [ 105 ].…”

‘Evidence‐based implementation’ of paediatric asthma guidelines in a rural emergency department

“…There is also evidence 39 that patients want written instructions and advice for the first 24–48 h after an acute asthma attack, and a readily available pre‐formatted STAMP may have facilitated the increased compliance with this indicator. There is little role for antibiotic use in acute asthma, 40 and while antibiotic use dropped from 15% to 6% this did not reach statistical significance. The lack of statistical significance for this indicator may be due to the relatively low rates of prescribing, and hence good compliance to begin with.…”

Management of severe asthma exacerbation: guidelines from the Société Française de Médecine d’Urgence, the Société de Réanimation de Langue Française and the French Group for Pediatric Intensive Care and Emergencies

“…An older placebo-controlled trial showed no symptomatic benefit of antibiotic therapy with amoxicillin in an adult population [59]. A meta-analysis including trials in children and adults was also negative [60]. In conclusion, there is no argument encouraging the routine administration of penicillin or of macrolides to adults with SAE requiring hospitalization.…”

An integrative review of systematic reviews related to the management of breathlessness in respiratory illnesses

“…Treatments included: anti-leukotrienes [ 64 , 65 ]; beta-agonists (inhaled/non-inhaled) [ 61 - 63 , 66 - 75 ]; allergen immunotherapy [ 76 ]; anti-IgE [ 77 ]; antibiotics [ 78 ]; anti-cholinergics [ 57 ]; azathioprine [ 79 ]; beclomethasone [ 80 - 82 ]; budesonide [ 83 , 84 ]; caffeine [ 85 ]; beta-blockers [ 58 ]; chloroquine [ 86 ]; corticosteroids (inhaled/non-inhaled) [ 59 , 60 , 87 - 91 ]; cyclosporine [ 92 ]; fluticasone [ 93 - 96 ]; anti-gastro-oesophageal reflux treatment [ 97 ]; gold [ 98 ]; inhaled/non-inhaled magnesium sulphate [ 98 , 100 ]; macrolides [ 101 , 102 ]; methotrexate [ 103 ]; oxatomide [ 104 ]; and tailored interventions based on sputum eosinophils [ 105 ].…”

‘Evidence‐based implementation’ of paediatric asthma guidelines in a rural emergency department

“…There is also evidence 39 that patients want written instructions and advice for the first 24–48 h after an acute asthma attack, and a readily available pre‐formatted STAMP may have facilitated the increased compliance with this indicator. There is little role for antibiotic use in acute asthma, 40 and while antibiotic use dropped from 15% to 6% this did not reach statistical significance. The lack of statistical significance for this indicator may be due to the relatively low rates of prescribing, and hence good compliance to begin with.…”

Management of severe asthma exacerbation: guidelines from the Société Française de Médecine d’Urgence, the Société de Réanimation de Langue Française and the French Group for Pediatric Intensive Care and Emergencies

“…An older placebo-controlled trial showed no symptomatic benefit of antibiotic therapy with amoxicillin in an adult population [59]. A meta-analysis including trials in children and adults was also negative [60]. In conclusion, there is no argument encouraging the routine administration of penicillin or of macrolides to adults with SAE requiring hospitalization.…”

An integrative review of systematic reviews related to the management of breathlessness in respiratory illnesses

“…Treatments included: anti-leukotrienes [ 64 , 65 ]; beta-agonists (inhaled/non-inhaled) [ 61 - 63 , 66 - 75 ]; allergen immunotherapy [ 76 ]; anti-IgE [ 77 ]; antibiotics [ 78 ]; anti-cholinergics [ 57 ]; azathioprine [ 79 ]; beclomethasone [ 80 - 82 ]; budesonide [ 83 , 84 ]; caffeine [ 85 ]; beta-blockers [ 58 ]; chloroquine [ 86 ]; corticosteroids (inhaled/non-inhaled) [ 59 , 60 , 87 - 91 ]; cyclosporine [ 92 ]; fluticasone [ 93 - 96 ]; anti-gastro-oesophageal reflux treatment [ 97 ]; gold [ 98 ]; inhaled/non-inhaled magnesium sulphate [ 98 , 100 ]; macrolides [ 101 , 102 ]; methotrexate [ 103 ]; oxatomide [ 104 ]; and tailored interventions based on sputum eosinophils [ 105 ].…”