Antibiotic resistance related to biofilm formation in Streptococcus suis

Li, Yang; Jin, Muchun; Li, Jinpeng; Grenier, Daniel; Wang, Yang

doi:10.1007/s00253-020-10873-9

Cited by 22 publications

(23 citation statements)

References 97 publications

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“…Five ICE families (defined by their conjugation genes) carrying AMR genes have been described in S. suis : elements of the Tn 5252 , Tn 1549 , and Tn 916 families; elements related to Tn GBS2 ; and ICEs integrated in the lysS gene related to ICE vanG . These various ICEs carrying AMR genes are presented in Figure 3 [ 25 , 26 , 29 , 30 , 33 , 42 , 76 , 77 ]. Until now, only ICEs of the Tn 5252 family have been studied experimentally to evaluate their mobility in S. suis [ 12 , 23 , 25 , 30 , 33 , 57 , 77 ].…”

Section: Dissemination Of Amr Genes Through Horizontal Gene Transfer In S Suismentioning

confidence: 99%

“…These various ICEs carrying AMR genes are presented in Figure 3 [ 25 , 26 , 29 , 30 , 33 , 42 , 76 , 77 ]. Until now, only ICEs of the Tn 5252 family have been studied experimentally to evaluate their mobility in S. suis [ 12 , 23 , 25 , 30 , 33 , 57 , 77 ].…”

Section: Dissemination Of Amr Genes Through Horizontal Gene Transfer In S Suismentioning

confidence: 99%

“…Within this biofilm and generally in the environment, the bacteria communicate with each other through quorum sensing. Quorum sensing is an intercellular communication system used by many bacteria including S. suis [ 77 , 86 , 87 , 88 ]. When the concentration of signaling molecules, such as the LuxS autoinducer-2, reaches a threshold level, bacteria can induce the expression of genes that participate to diverse processes, in particular, biofilm formation and antibiotic resistance.…”

Section: Formation Of Biofilm and Antimicrobial Resistancementioning

confidence: 99%

“…Strains with a LuxS quorum sensing system showed an increased susceptibility to fluoroquinolones [ 87 ], while addition of exogenous AI-2 signaling molecule increases resistance to tetracycline though a regulatory effect on Tn 916 carrying tet (M) [ 89 ]. Other molecules, in particular sub-inhibitory concentrations of amoxicillin, lincomycin, and oxytetracycline, were described in the literature to induce biofilm formation [ 77 , 90 ]. In 2020, Wang and collaborators suggest a possible cooperation between S. suis and Actinobacillus pleuropneumoniae [ 88 ].…”

Section: Formation Of Biofilm and Antimicrobial Resistancementioning

confidence: 99%

“…They found an increase in antibiotic resistance when the two bacteria are co-cultured in biofilms. Different mechanisms are responsible for antibiotic resistance of S. suis embedded in biofilm: high expression of EPS, efflux pumps, reduced growth and metabolic adaptation, stress response induction, high probability of gene mutations, and horizontal gene transfer [ 77 ].…”

Section: Formation Of Biofilm and Antimicrobial Resistancementioning

confidence: 99%

See 4 more Smart Citations

Update on the Mechanisms of Antibiotic Resistance and the Mobile Resistome in the Emerging Zoonotic Pathogen Streptococcus suis

Dechêne-Tempier

Marois-Créhan²,

Libante

et al. 2021

Microorganisms

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Streptococcus suis is a zoonotic pathogen causing important economic losses in swine production. The most commonly used antibiotics in swine industry are tetracyclines, beta-lactams, and macrolides. Resistance to these antibiotics has already been observed worldwide (reaching high rates for macrolides and tetracyclines) as well as resistance to aminoglycosides, fluoroquinolones, amphenicols, and glycopeptides. Most of the resistance mechanisms are encoded by antibiotic resistance genes, and a large part are carried by mobile genetic elements (MGEs) that can be transferred through horizontal gene transfer. This review provides an update of the resistance genes, their combination in multidrug isolates, and their localization on MGEs in S. suis. It also includes an overview of the contribution of biofilm to antimicrobial resistance in this bacterial species. The identification of resistance genes and study of their localization in S. suis as well as the environmental factors that can modulate their dissemination appear essential in order to decipher the role of this bacterium as a reservoir of antibiotic genes for other species.

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Section: Dissemination Of Amr Genes Through Horizontal Gene Transfer In S Suismentioning

confidence: 99%

Section: Dissemination Of Amr Genes Through Horizontal Gene Transfer In S Suismentioning

confidence: 99%

Section: Formation Of Biofilm and Antimicrobial Resistancementioning

confidence: 99%

Section: Formation Of Biofilm and Antimicrobial Resistancementioning

confidence: 99%

Section: Formation Of Biofilm and Antimicrobial Resistancementioning

confidence: 99%

See 3 more Smart Citations

Update on the Mechanisms of Antibiotic Resistance and the Mobile Resistome in the Emerging Zoonotic Pathogen Streptococcus suis

Dechêne-Tempier

Marois-Créhan²,

Libante

et al. 2021

Microorganisms

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Strategies to Improve the Potency of Oxazolidinones towards Bacterial Biofilms

Ndukwe

Wiedbrauk

Boase

et al. 2022

Chemistry An Asian Journal

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Biofilms are part of the natural lifecycle of bacteria and are known to cause chronic infections that are difficult to treat. Most antibiotics are developed and tested against bacteria in the planktonic state and are ineffective against bacterial biofilms. The oxazolidinones, including the last resort drug linezolid, are one of the main classes of synthetic antibiotics progressed to clinical use in the last 50 years. They have a unique mechanism of action and only develop low levels of resistance in the clinical setting. With the aim of providing insight into strategies to design more potent antibiotic compounds with activity against bacterial biofilms, we review the biofilm activity of clinically approved oxazolidinones and report on structural modifications to oxazolidinones and their delivery systems which lead to enhanced anti‐biofilm activity.

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Streptococcus vaginalis sp. nov., a novel bacterial species isolated from vaginal swabs of a pregnant woman with diabetes

et al. 2021

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Sequences targeted at the V3 and V4 16S rRNA hypervariable regions of a streptococcal strain (P1L01 T ) isolated from vaginal swabs of a pregnant woman with diabetes were 100% similar to those of Streptococcus anginosus subsp. whileyi. However, phylogenetic analysis based on 16S rRNA full-gene sequencing (1562 bp) revealed highest sequence similarity to Streptococcus periodonticum (98.65%), followed by Streptococcus anginosus subsp. whileyi (98.65 %), and Streptococcus anginosus subsp. anginosus (98.44%). Phylogenies of housekeeping genes rpoB and groEL were compared to improve classi cation, and the results showed a clear separation between strain P1L01 T and closely related Streptococcus type strains. The complete genome of strain P1L01 T consisted of 2,108,769 bp with a G+C content of 38.5 mol%. Average nucleotide identity values, based on genome sequencing, between strain P1L01 T and Streptococcus periodonticum KCOM 2412 T , Streptococcus anginosus subsp. whileyi CCUG 39159 T , and Streptococcus anginosus subsp. anginosus NCTC 10713 T were 95.48%, 94.33%, and 95.28%, respectively. The highest in silico DNA-DNA hybridization value with respect to the closest species was 66.2%, i.e., below the species cut-off of 70% hybridization. The main cellular fatty acids of strain P1L01 T were 16:0, 18:1ω7c, and 14:0. On the basis of phylogenetic, genotypic and phenotypic data, we propose to classify this isolate as representative of a novel species of the genus Streptococcus, Streptococcus vaginalis sp. nov., in reference to its isolation from vaginal swabs, with strain P1L01 T (=NBRC 114754 T = BCRC 81289 T ) as the type strain.

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Antibiotic resistance related to biofilm formation in Streptococcus suis

Cited by 22 publications

References 97 publications

Update on the Mechanisms of Antibiotic Resistance and the Mobile Resistome in the Emerging Zoonotic Pathogen Streptococcus suis

Update on the Mechanisms of Antibiotic Resistance and the Mobile Resistome in the Emerging Zoonotic Pathogen Streptococcus suis

Strategies to Improve the Potency of Oxazolidinones towards Bacterial Biofilms

Streptococcus vaginalis sp. nov., a novel bacterial species isolated from vaginal swabs of a pregnant woman with diabetes

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