Antibiotic prophylaxis of wound infections in skin surgery

A prospective study of the incidence of complications associated with dermatological surgery

“…In the majority of dermatological surgery procedures, prophylaxis is not needed because the overall incidence of infection is low. However, specific factors including the type of procedure or the overall patient health status may increase the risk of wound infection, so a possible benefit might be achieved by the administration of preoperative antibiotics 12,13 . The duration of the operation was related to the incidence of subsequent wound infection, in accordance with other reported (nonskin) surgical practices 14 .…”

An Update on Antibiotic Prophylaxis in Dermatologic Surgery

“…Two studies have shown oral AP significantly reduced DSSI [15,72]. Large RCTs have confirmed the effectiveness of intra-incisional [78,80] and intramuscular [78,81] AP against DSSI. Intravenous AP has been found to reduce infection rates following skin grafts [24,82] but not hand surgery.…”

A Clinical Prediction Model for Surgical Site Infections in Dermatological Surgery

“…Effectiveness of the intervention is not accounted for by net benefit analysis. There are 3 trials in the literature assessing the most effective method and optimal timing of antibiotic prophylaxis in dermatological surgery (21)(22)(23). The first study performed by Bencini et al (21) randomized patients receiving skin surgery into 4 groups, with group A not receiving prophylaxis, group B receiving antibiotics for 3 days after surgery, group C receiving antibiotic powder during surgery, and group D receiving prophylaxis 2 days before and 2 days after surgery.…”