Antibiotic prophylaxis for operative vaginal delivery

Abstract

One small trial was identified reporting only two outcomes. Evidence from this single trial suggests that antibiotic prophylaxis may lead to little or no difference in endometritis or maternal length of stay. There were no data on any other outcomes to evaluate the impact of antibiotic prophylaxis after operative vaginal delivery. Future research on antibiotic prophylaxis for operative vaginal delivery is needed to conclude whether it is useful for reducing postpartum morbidity.

Association of white blood cell count after operative vaginal delivery with maternal adverse outcome: A retrospective cohort study

“…However, there was no significant association of WBC count with incidence of the primary outcome. The incidence of the primary outcome in the present study was similar to the reported incidences (3.5% to 16%) of postpartum infection or endometritis [22].…”

Association of white blood cell count after operative vaginal delivery with maternal adverse outcome: A retrospective cohort study

“…However, there was no significant association of WBC count with incidence of the primary outcome. The incidence of the primary outcome in the present study was similar to the reported incidences (3.5% to 16%) of postpartum infection or endometritis [22].…”

Use of Prophylactic Antibiotics in Third and Fourth Degree of Perineal Rupture

“…In the postpartum examination two weeks in a row, a comparison of the percentage of complications between the treatment and control groups was 8.20% versus 24.10%, the risk ratio (RR) was 0.34, then the 95% confidence interval (CL) was 0.12-0.96. 37 And, the same thing was also obtained by Liabsuetrakul et al (2020) who stated that prophylactic antibiotics reduced the risk of infection of superficial perineal rupture with an RR of 0.53, then 95% CL of 0.40-0.69 and the administration of prophylactic antibiotics for rupture deep perineum with RR of 0.46 and 95% CL 0.31-0.69. Based on these data indicate that prophylactic antibiotics can prevent complications of third and fourthdegree perineal rupture.…”

Antibiotic Use in Caesarean Section among Obstetricians and Gynaecologists in the Second Largest City in Indonesia

“…Cochrane studies have shown that using prophylactic antibiotics in a CS can reduce superfi cial perineal wound infection, deep perineal wound infection, and probably wound breakdown. 19 However, the choice of prophylactic antibiotic administered is still highly varied. Most obstetricians used cefazoline (1st generation cephalosporin) as an intravenous prophylactic antibiotic at a dose of 2 g (93.2%); the remaining used 1-2 g. The rest use various antibiotics, including 2nd and 3rd generation cephalosporins.…”

Association of white blood cell count after operative vaginal delivery with maternal adverse outcome: A retrospective cohort study

“…However, there was no significant association of WBC count with incidence of the primary outcome. The incidence of the primary outcome in the present study was similar to the reported incidences (3.5% to 16%) of postpartum infection or endometritis [22].…”

Use of Prophylactic Antibiotics in Third and Fourth Degree of Perineal Rupture

“…In the postpartum examination two weeks in a row, a comparison of the percentage of complications between the treatment and control groups was 8.20% versus 24.10%, the risk ratio (RR) was 0.34, then the 95% confidence interval (CL) was 0.12-0.96. 37 And, the same thing was also obtained by Liabsuetrakul et al (2020) who stated that prophylactic antibiotics reduced the risk of infection of superficial perineal rupture with an RR of 0.53, then 95% CL of 0.40-0.69 and the administration of prophylactic antibiotics for rupture deep perineum with RR of 0.46 and 95% CL 0.31-0.69. Based on these data indicate that prophylactic antibiotics can prevent complications of third and fourthdegree perineal rupture.…”

Antibiotic Use in Caesarean Section among Obstetricians and Gynaecologists in the Second Largest City in Indonesia

“…Cochrane studies have shown that using prophylactic antibiotics in a CS can reduce superfi cial perineal wound infection, deep perineal wound infection, and probably wound breakdown. 19 However, the choice of prophylactic antibiotic administered is still highly varied. Most obstetricians used cefazoline (1st generation cephalosporin) as an intravenous prophylactic antibiotic at a dose of 2 g (93.2%); the remaining used 1-2 g. The rest use various antibiotics, including 2nd and 3rd generation cephalosporins.…”

Association of white blood cell count after operative vaginal delivery with maternal adverse outcome: A retrospective cohort study

“…However, there was no significant association of WBC count with incidence of the primary outcome. The incidence of the primary outcome in the present study was similar to the reported incidences (3.5% to 16%) of postpartum infection or endometritis [22].…”

Use of Prophylactic Antibiotics in Third and Fourth Degree of Perineal Rupture

“…In the postpartum examination two weeks in a row, a comparison of the percentage of complications between the treatment and control groups was 8.20% versus 24.10%, the risk ratio (RR) was 0.34, then the 95% confidence interval (CL) was 0.12-0.96. 37 And, the same thing was also obtained by Liabsuetrakul et al (2020) who stated that prophylactic antibiotics reduced the risk of infection of superficial perineal rupture with an RR of 0.53, then 95% CL of 0.40-0.69 and the administration of prophylactic antibiotics for rupture deep perineum with RR of 0.46 and 95% CL 0.31-0.69. Based on these data indicate that prophylactic antibiotics can prevent complications of third and fourthdegree perineal rupture.…”

Antibiotic Use in Caesarean Section among Obstetricians and Gynaecologists in the Second Largest City in Indonesia

“…Cochrane studies have shown that using prophylactic antibiotics in a CS can reduce superfi cial perineal wound infection, deep perineal wound infection, and probably wound breakdown. 19 However, the choice of prophylactic antibiotic administered is still highly varied. Most obstetricians used cefazoline (1st generation cephalosporin) as an intravenous prophylactic antibiotic at a dose of 2 g (93.2%); the remaining used 1-2 g. The rest use various antibiotics, including 2nd and 3rd generation cephalosporins.…”