Antibiotic and other lock treatments for tunnelled central venous catheter related infections in children with cancer

High Prevalence of Multidrug-Resistant Bacteria in the Centre Hospitalier et Universitaire de la Mère et de l’Enfant Lagune (CHU-MEL) Reveals Implications of Poor Hygiene Practices in Healthcare

“…A significant correlation was reported between the occurrence of catheterrelated bacteremia and the duration of catheterization. Many authors have come to the same conclusion for catheter-related bacteremias [25,27,28]. Merrer [27] explains this fact by the multiplication of potentially septic manipulations from the connector (faucets, infusions …).…”

High Prevalence of Multidrug-Resistant Bacteria in the Centre Hospitalier et Universitaire de la Mère et de l’Enfant Lagune (CHU-MEL) Reveals Implications of Poor Hygiene Practices in Healthcare

“…A significant correlation was reported between the occurrence of catheterrelated bacteremia and the duration of catheterization. Many authors have come to the same conclusion for catheter-related bacteremias [25,27,28]. Merrer [27] explains this fact by the multiplication of potentially septic manipulations from the connector (faucets, infusions …).…”

Comparing success rates in central venous catheter salvage for catheter-related bloodstream infections in adult patients on home parenteral nutrition: a systematic review and meta-analysis

“…Studies incorporating different patient populations were only included if the text outlined that patients on parenteral nutrition were included. Studies only containing children were excluded in order to limit the heterogeneity of the patient population and because of expected differences in CRBSI etiology, diagnosis, and management ( 22 , 23 ). When distinct publications had partly overlapping data due to the same patients’ inclusion, the results were either combined or collected from the most extensive study to avoid duplicate data.…”

Long‐term IV access in paediatrics ‐ why, what, where, who and how

“…None of these actions have single handily contributed to an overall pronounced effect and the use of systemic antibiotics as well as antibiotic impregnated catheters is not routinely recommended. However, combining the previous mentioned approaches with a number of contributing factors (bundle strategy) such as the use of systematic site disinfection (eg, chlorhexidine 2% in alcohol), focus on hand hygiene and sterile techniques when using CVCs has had the most pronounced impact 6,19‐22 . The subject of CLABSI is comprehensive and will therefore not be covered in full details in this review.…”

High Prevalence of Multidrug-Resistant Bacteria in the Centre Hospitalier et Universitaire de la Mère et de l’Enfant Lagune (CHU-MEL) Reveals Implications of Poor Hygiene Practices in Healthcare

“…A significant correlation was reported between the occurrence of catheterrelated bacteremia and the duration of catheterization. Many authors have come to the same conclusion for catheter-related bacteremias [25,27,28]. Merrer [27] explains this fact by the multiplication of potentially septic manipulations from the connector (faucets, infusions …).…”

Comparing success rates in central venous catheter salvage for catheter-related bloodstream infections in adult patients on home parenteral nutrition: a systematic review and meta-analysis

“…Studies incorporating different patient populations were only included if the text outlined that patients on parenteral nutrition were included. Studies only containing children were excluded in order to limit the heterogeneity of the patient population and because of expected differences in CRBSI etiology, diagnosis, and management ( 22 , 23 ). When distinct publications had partly overlapping data due to the same patients’ inclusion, the results were either combined or collected from the most extensive study to avoid duplicate data.…”

Long‐term IV access in paediatrics ‐ why, what, where, who and how

“…None of these actions have single handily contributed to an overall pronounced effect and the use of systemic antibiotics as well as antibiotic impregnated catheters is not routinely recommended. However, combining the previous mentioned approaches with a number of contributing factors (bundle strategy) such as the use of systematic site disinfection (eg, chlorhexidine 2% in alcohol), focus on hand hygiene and sterile techniques when using CVCs has had the most pronounced impact 6,19‐22 . The subject of CLABSI is comprehensive and will therefore not be covered in full details in this review.…”

High Prevalence of Multidrug-Resistant Bacteria in the Centre Hospitalier et Universitaire de la Mère et de l’Enfant Lagune (CHU-MEL) Reveals Implications of Poor Hygiene Practices in Healthcare

“…A significant correlation was reported between the occurrence of catheterrelated bacteremia and the duration of catheterization. Many authors have come to the same conclusion for catheter-related bacteremias [25,27,28]. Merrer [27] explains this fact by the multiplication of potentially septic manipulations from the connector (faucets, infusions …).…”

Comparing success rates in central venous catheter salvage for catheter-related bloodstream infections in adult patients on home parenteral nutrition: a systematic review and meta-analysis

“…Studies incorporating different patient populations were only included if the text outlined that patients on parenteral nutrition were included. Studies only containing children were excluded in order to limit the heterogeneity of the patient population and because of expected differences in CRBSI etiology, diagnosis, and management ( 22 , 23 ). When distinct publications had partly overlapping data due to the same patients’ inclusion, the results were either combined or collected from the most extensive study to avoid duplicate data.…”

Long‐term IV access in paediatrics ‐ why, what, where, who and how

“…None of these actions have single handily contributed to an overall pronounced effect and the use of systemic antibiotics as well as antibiotic impregnated catheters is not routinely recommended. However, combining the previous mentioned approaches with a number of contributing factors (bundle strategy) such as the use of systematic site disinfection (eg, chlorhexidine 2% in alcohol), focus on hand hygiene and sterile techniques when using CVCs has had the most pronounced impact 6,19‐22 . The subject of CLABSI is comprehensive and will therefore not be covered in full details in this review.…”