Antibacterial silk sericin/poly (vinyl alcohol) hydrogel with antifungal property for potential infected large burn wound healing: Systemic evaluation

Bakadia, Bianza Moïse; Lamboni, Lallepak; Ahmed, Abeer Ahmed Qaed; Zheng, Ruizhu; Boni, B; Shi, Zhijun; Song, Shilin; Souho, Tiatou; Mukole, Biampata Mutu; Qi, Fuyu; Yang, Guang

doi:10.1016/j.smaim.2022.07.002

Cited by 33 publications

(32 citation statements)

References 72 publications

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“…53 The hydrogels prepared in this study show significant antifungal activity against Candida albicans , and these results are in good agreement with the gels reported in literature, e.g. , the zone of inhibition characteristics of the PVA/silk sericin hydrogel 54 and the chitosan/vanillin 55 hydrogel against the Candida albicans fungal strain are comparable to our study. The zones of inhibition around the hydrogel discs can be seen in Fig.…”

Section: Resultssupporting

confidence: 92%

A composite polyvinyl alcohol–medicinal plant extract crosslinked hydrogel: a novel soft system with excellent rhodamine B adsorption and significant antifungal activity

Tak,

Rashid,

Ahangar

et al. 2023

New J. Chem.

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Section: Resultssupporting

confidence: 92%

A composite polyvinyl alcohol–medicinal plant extract crosslinked hydrogel: a novel soft system with excellent rhodamine B adsorption and significant antifungal activity

Tak,

Rashid,

Ahangar

et al. 2023

New J. Chem.

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“…A recent study 139 discusses the design, preparation, and characterization of hydrogels using different materials such as silk fibroin, sericin, and poly(vinyl alcohol) (Figure 8). The incorporation of antibiotics and other antimicrobial agents into the hydrogels enhances their antibacterial and antifungal properties.…”

Section: Modifications Of Silk Sericinmentioning

confidence: 99%

Waste to Wealth: Exploring the Versatile Prospects of Discarded Silk Sericin

Sabu Mathew,

Maria,

Allardyce

et al. 2024

ACS Sustainable Chem. Eng.

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Biorefinery, the process of converting biomass to valueadded materials, is gaining significant interest because of the depletion of natural resources and an increasing awareness of the need for sustainable development and material production. Silk sericin, an abundantly available byproduct of the sericulture industry, has been identified for biorefinery usage since it is biodegradable, bioavailable, pH and temperatureresponsive, naturally photoluminescent, has antioxidant properties, and is a GRAS and FDA-safe food additive. This Perspective examines the properties of sericin and its sources and discusses currently explored applications, including as a delivery system for drugs or genetic material, for wound healing, tissue engineering, media supplements, cosmetology, packaging materials, edible coating, and as bio adhesives. This Perspective examines the sources of sericin, its properties, and some of the currently explored applications. These include biomedical applications such as a delivery system for drugs or genetic material, wound healing, tissue engineering, media supplements, cosmetology, packaging materials, edible coating, and as bio adhesives. Finally, we highlight the recent developments in sericin modification to functionalize it for specific applications; this is a promising future direction that will further enhance the potential use of this valuable biomass.

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“…The hydrogel also showed sustained SS and AZM releases, cytocompatibility on keratinocytes and fibroblasts, as well as skin adhesion ability when freeze-dried. Regarding specifically the in vivo study using an infected mouse full-thickness burn model with a 10% total body surface area, the hydrogel presented a better burn wound healing effect than the commercial Tegaderm™ film dressing, thus minimizing systemic burn effects [ 49 ].…”

Section: Treatments For Topical Infected Woundsmentioning

confidence: 99%

The Use of Proteins, Lipids, and Carbohydrates in the Management of Wounds

et al. 2023

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Despite the fact that skin has a stronger potential to regenerate than other tissues, wounds have become a serious healthcare issue. Much effort has been focused on developing efficient therapeutical approaches, especially biological ones. This paper presents a comprehensive review on the wound healing process, the classification of wounds, and the particular characteristics of each phase of the repair process. We also highlight characteristics of the normal process and those involved in impaired wound healing, specifically in the case of infected wounds. The treatments discussed here include proteins, lipids, and carbohydrates. Proteins are important actors mediating interactions between cells and between them and the extracellular matrix, which are essential interactions for the healing process. Different strategies involving biopolymers, blends, nanotools, and immobilizing systems have been studied against infected wounds. Lipids of animal, mineral, and mainly vegetable origin have been used in the development of topical biocompatible formulations, since their healing, antimicrobial, and anti-inflammatory properties are interesting for wound healing. Vegetable oils, polymeric films, lipid nanoparticles, and lipid-based drug delivery systems have been reported as promising approaches in managing skin wounds. Carbohydrate-based formulations as blends, hydrogels, and nanocomposites, have also been reported as promising healing, antimicrobial, and modulatory agents for wound management.

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Antibacterial silk sericin/poly (vinyl alcohol) hydrogel with antifungal property for potential infected large burn wound healing: Systemic evaluation

Cited by 33 publications

References 72 publications

A composite polyvinyl alcohol–medicinal plant extract crosslinked hydrogel: a novel soft system with excellent rhodamine B adsorption and significant antifungal activity

A composite polyvinyl alcohol–medicinal plant extract crosslinked hydrogel: a novel soft system with excellent rhodamine B adsorption and significant antifungal activity

Waste to Wealth: Exploring the Versatile Prospects of Discarded Silk Sericin

The Use of Proteins, Lipids, and Carbohydrates in the Management of Wounds

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