Antibacterial peptides isolated from insects

From individual to collective immunity: The role of the venom as antimicrobial agent in the Stenogastrinae wasp societies

“…Moreover, the investment of an hover wasp, insofar as social, in a individual immunity may raise a form of the so called ''herd immunity'' by reducing the risk of infection for neighbouring susceptible individuals (Frank, 1998). Since, resistance to parasitic infections has been one of the major factors that favoured the evolution of social insects (Otvos, 2000), it is likely that individuals gain immune benefits as a consequence of colony level selection rather than simply as a by-product of nestmate's personal immunity, being an instance of social immunity (sensu Cotter and Kilner, 2011). Also in M. drewseni, where the level of social behaviour is between the lowest in the subfamily, with colonies counting no more than one mother and one-two offspring (Turillazzi, 1990), the ''herd immunity'' can fall within the broader definition of social immunity given by Cotter and Kilner (2011).…”

From individual to collective immunity: The role of the venom as antimicrobial agent in the Stenogastrinae wasp societies

“…Moreover, the investment of an hover wasp, insofar as social, in a individual immunity may raise a form of the so called ''herd immunity'' by reducing the risk of infection for neighbouring susceptible individuals (Frank, 1998). Since, resistance to parasitic infections has been one of the major factors that favoured the evolution of social insects (Otvos, 2000), it is likely that individuals gain immune benefits as a consequence of colony level selection rather than simply as a by-product of nestmate's personal immunity, being an instance of social immunity (sensu Cotter and Kilner, 2011). Also in M. drewseni, where the level of social behaviour is between the lowest in the subfamily, with colonies counting no more than one mother and one-two offspring (Turillazzi, 1990), the ''herd immunity'' can fall within the broader definition of social immunity given by Cotter and Kilner (2011).…”

Antimicrobial Peptides: Synthesis and Antibacterial Activity of Linear and Cyclic Drosocin and Apidaecin 1b Analogues

“…More flexible cycles, such as peptide XIII c , can preserve some antimicrobial activity probably because they maintain an extended domain in the central part of the peptide. This structural hypothesis is supported by NMR conformational studies recently reported for drosocin and pyrrhocoricin …”

Interaction between Heat Shock Proteins and Antimicrobial Peptides

“…In conclusion, the antibacterial peptide drug leads need to be tested for their efficacy both in vitro and in vivo before any additional modification in their composition is initiated. Actually this recommendation coincides with our latest finding as to low in vitro activity of the antibacterial peptides does not necessarily indicate negligible in vivo efficacy (56).…”

From individual to collective immunity: The role of the venom as antimicrobial agent in the Stenogastrinae wasp societies

“…Moreover, the investment of an hover wasp, insofar as social, in a individual immunity may raise a form of the so called ''herd immunity'' by reducing the risk of infection for neighbouring susceptible individuals (Frank, 1998). Since, resistance to parasitic infections has been one of the major factors that favoured the evolution of social insects (Otvos, 2000), it is likely that individuals gain immune benefits as a consequence of colony level selection rather than simply as a by-product of nestmate's personal immunity, being an instance of social immunity (sensu Cotter and Kilner, 2011). Also in M. drewseni, where the level of social behaviour is between the lowest in the subfamily, with colonies counting no more than one mother and one-two offspring (Turillazzi, 1990), the ''herd immunity'' can fall within the broader definition of social immunity given by Cotter and Kilner (2011).…”

Antimicrobial Peptides: Synthesis and Antibacterial Activity of Linear and Cyclic Drosocin and Apidaecin 1b Analogues

“…More flexible cycles, such as peptide XIII c , can preserve some antimicrobial activity probably because they maintain an extended domain in the central part of the peptide. This structural hypothesis is supported by NMR conformational studies recently reported for drosocin and pyrrhocoricin …”

Interaction between Heat Shock Proteins and Antimicrobial Peptides

“…In conclusion, the antibacterial peptide drug leads need to be tested for their efficacy both in vitro and in vivo before any additional modification in their composition is initiated. Actually this recommendation coincides with our latest finding as to low in vitro activity of the antibacterial peptides does not necessarily indicate negligible in vivo efficacy (56).…”

From individual to collective immunity: The role of the venom as antimicrobial agent in the Stenogastrinae wasp societies

“…Moreover, the investment of an hover wasp, insofar as social, in a individual immunity may raise a form of the so called ''herd immunity'' by reducing the risk of infection for neighbouring susceptible individuals (Frank, 1998). Since, resistance to parasitic infections has been one of the major factors that favoured the evolution of social insects (Otvos, 2000), it is likely that individuals gain immune benefits as a consequence of colony level selection rather than simply as a by-product of nestmate's personal immunity, being an instance of social immunity (sensu Cotter and Kilner, 2011). Also in M. drewseni, where the level of social behaviour is between the lowest in the subfamily, with colonies counting no more than one mother and one-two offspring (Turillazzi, 1990), the ''herd immunity'' can fall within the broader definition of social immunity given by Cotter and Kilner (2011).…”

Antimicrobial Peptides: Synthesis and Antibacterial Activity of Linear and Cyclic Drosocin and Apidaecin 1b Analogues

“…More flexible cycles, such as peptide XIII c , can preserve some antimicrobial activity probably because they maintain an extended domain in the central part of the peptide. This structural hypothesis is supported by NMR conformational studies recently reported for drosocin and pyrrhocoricin …”

Interaction between Heat Shock Proteins and Antimicrobial Peptides

“…In conclusion, the antibacterial peptide drug leads need to be tested for their efficacy both in vitro and in vivo before any additional modification in their composition is initiated. Actually this recommendation coincides with our latest finding as to low in vitro activity of the antibacterial peptides does not necessarily indicate negligible in vivo efficacy (56).…”