Antibacterial and Antibiofilm Effects of Boron on Different Bacteria

Sayın, Zafer; Uçan, Uçkun Sait; Sakmanoğlu, Aslı

doi:10.1007/s12011-016-0637-z

Cited by 60 publications

(41 citation statements)

References 17 publications

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“…Boron (B) is an essential plant micronutrient, but excessive B is toxic to both of plants (Aitken & McCallum, ) and of bacteria (Mansour, Bradford, & Venkatesan, ; Sayin, Ucan, & Sakmanoglu, ). A significant decrease in microbial diversity and richness is observed in the rhizospheric soil with high B content (Nelson & Mele, ).…”

Section: Discussionmentioning

confidence: 99%

Continuous‐cropping tobacco caused variance of chemical properties and structure of bacterial network in soils

et al. 2018

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Continuous cropping of the same crop leads to land degradation. This is also called the continuous-cropping obstacle. Here, we investigated how long-term continuous cropping of tobacco influences soil biochemical properties and bacterial networks in the mountain lands of China. Two different fields were sampled: one with 25 years of continuous cropping tobacco and one with noncontinuous cropping tobacco. Soil chemical and biological properties were measured including available phosphorus and potassium, soil organic matter, pH, alkali-hydrolysable nitrogen, micronutrients contents, and activity of urease, catalase, invertase, and phosphatase as well as tobacco agronomic characteristics. Bacterial communities of the two different soils were sequenced by metabarcoding of the 16S ribosomal RNA, and, with these data, network analysis was done. Soil chemical properties and tobacco agronomical properties were negatively affected by the continuous-cropping obstacle, and this treatment has a less complex network (less modules, nodes, and connectivity) than the soil with noncontinuous cropping treatment. For continuous cropping, there were less generalists, which were key species that connect network, than noncontinuous cropping.Moreover, the taxonomic composition of bacterial network was different in the two different treatments. In the continuous-cropping network, 40% nodes had negative interactions, suggesting that more competition or antagonism existed among bacterial species. It concluded that continuous cropping has a detrimental effect on soil chemical and that the bacterial network properties under continuous cropping are more sensitive to soil variables (so more unstable and inefficient) because there are less bacterial species that interact each other and this is due to limited nutrients or excessive toxic nutrient.This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Section: Discussionmentioning

confidence: 99%

Continuous‐cropping tobacco caused variance of chemical properties and structure of bacterial network in soils

et al. 2018

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“…It is necessary for human and animal cell functions, as it binds to cis-hydroxyl groups on cell membranes (20,21). Boron has increasingly been studied in new areas of research (7,8,22). Based on their principal mechanism of action, one of two groups of vaccine adjuvants is called "immune potentiators" (23).…”

Section: Discussionmentioning

confidence: 99%

“…Such assessments could be strengthened by measuring additional cytokines. BA in the Kangal cell cultures may predominantly drive proliferation of B lymphocytes, since IL-4 is also referred to as B cell growth factor (BCGF) (7). More comprehensive measurements of additional cytokines over a time course should be undertaken in the future.…”

Section: Discussionmentioning

confidence: 99%

Proliferation effects of phenylboronic acid and boric acid on canine peripheral blood mononuclear cells

Uçan¹,

Sayın²

2019

Turk J Vet Anim Sci

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The effects of phenylboronic acid (PBA) and boric acid (BA) on the proliferation of canine peripheral blood mononuclear cells (PBMCs) were investigated. Treatment of PBMCs from mixed breed dogs with PBA or BA (0.05 µg/mL) alone elicited blastogenic responses of 0.478 ± 0.438 and 0.499 ± 0.366, respectively. We observed an additive effect on proliferation when purebred Kangal PBMCs were cultured in a combination of BA (0.001 µg/mL) and the mitogenic lectin concanavalin A (1 µg/mL). However, the effects were not statistically significant. We detected varied IL-2 and IL-4 secretion in response to stimulation with boron-containing compounds. Our findings suggest that PBA induces canine PBMC proliferation, albeit less potently than lectins. However, boronic acid compounds may still prove beneficial as adjuvants to elicit cell proliferation and boost canine immune responses.

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“…Sayın ve ark. (2016) [29], borik asit molekülünün çeşitli bakterilerde biyofilm üzerine etkisini değerlendirdikleri çalışmalarında sadece P. aeruginosa ATCC 27853 suşunda biyofilm oluşumu üzerine etkili olmadığını tespit etmesine rağmen bu çalışmada biyofilm oluşumunu 2-NFBA %36, 4-BFBA %39, 4-KFBA %42, 4-FLFBA %30, 4-FFBA %35 ve 4-MFBA %36 oranında azalttığı tespit edilmiştir (Şekil3).…”

Section: Boronik Asit Moleküllerin Biyofilm Oluşumuna Etkisi (Effect unclassified

Effects of Boronic Acid Molecules on Production of Virulence Factors in Pseudomonas aeruginosa

Ulusoy

Akalın²

2018

Journal of Boron

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The intercellular communication (Quorum sensing) in bacteria is based on using small diffusible signal molecules called as autoinducers to communicate with each other. Studies have shown that QS controls a large number of microbial processes, including the expression of virulence factors. The aim of this work is to investigate the potential inhibitory effect of boronic acid molecules on the production of virulence factors controlled by the intercellular communication system in Pseudomonas aeruginosa. In this study, the effects of some boronic acid derivatives were investigated on the production of virulence factors (elastase and pyocyanin), biofilm formation and swarming motility in P. aeruginosa PA01. The results indicate that production of elastase and pyocyanin, the formation of biofilm and swarming motility were significantly reduced by 4-Bromofenilboronic acid. This study tends to support the potential inhibitory effects of boronic acid derivatives on the production of virulence factors in some pathogens such as P. aeruginosa.

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Antibacterial and Antibiofilm Effects of Boron on Different Bacteria

Cited by 60 publications

References 17 publications

Continuous‐cropping tobacco caused variance of chemical properties and structure of bacterial network in soils

Continuous‐cropping tobacco caused variance of chemical properties and structure of bacterial network in soils

Proliferation effects of phenylboronic acid and boric acid on canine peripheral blood mononuclear cells

Effects of Boronic Acid Molecules on Production of Virulence Factors in Pseudomonas aeruginosa

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