Antibacterial activity of diospyrin, isodiospyrin and bisisodiospyrin from the root of Diospyros piscatoria (Gurke) (Ebenaceae)

Cytotoxicity, early safety screening, and antimicrobial potential of minor oxime constituents of essential oils and aromatic extracts

“… Microorganism Compound MIC [mg/L] (mM) E .coli (−)-Camphor 75.50 (0.49) (−)-Camphor oxime 150.00 (0.90) Ampicillin 25.00 (0.07) 20 Gentamicin 20.00 (0.04) 20 L. pneumophila α-Ionone oxime 112.50 (0.54) β-Ionone 150.00 (0.78) β-Ionone oxime 37.50 (0.18) Dihydro-α-ionone oxime 150.00 (0.72) Dihydro-β-ionone 300.00 (1.54) Dihydro-β-ionone oxime 150.00 (0.72) β-Cyclocitral 300.00 (1.97) Gentamicin 0.39 (8.00 × 10 −4 ) 21 E. hirae α-Amylcinnamaldehyde oxime 150.00 (0.74) α-Hexylcinnamaldehyde oxime 42.18 (0.18) p -Tolualdehyde oxime 150.00 (1.11) α-Isomethylionone oxime 18.75 (0.08) Ciprofloxacin 8.00 (0.02) 22 B. cereus Pseudoionone oxime 150.00 (0.72) Gentamicin 2.00 (4.00 × 10 −3 ) 23 Ampicillin 1.00 (3.00 × 10 −3 ) 23 S. au...…”

Antitubercular and Antibacterial Activity of Quinonoid Natural Products Against Multi‐Drug Resistant Clinical Isolates

“…Among the tested quinonoids, diospyrin and emodin showed comparatively low activity with MIC range of 64 ->512, and 8 ->512 μg/mL, respectively. A previous report on diospyrin had indicated MIC value of 100-200 μg/mL against bacterial ATCC strains (Adeniyi et al, 2000). In an earlier study, the MIC of emodin was found to be 0.5 -2.0 μg/mL against Bacillus spp.…”

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“…However, it may be suggested that plant extracts exhibiting diameters of zones of inhibition >10 mm considered active. [33] In this line, it may be suggested that the extract and its fractions are better antimicrobial agents for various pathogenic fungus and bacteria. The pharmacological activities of the drug contributed to the presence of secondary metabolites.…”