Antibacterial Activity of Carica papaya Leaves and Allium sativum Cloves Alone and in Combination against Multiple Strains

Lonkala, Srividya; Reddy, A. Rama Narsimha

doi:10.5530/pj.2019.11.95

Cited by 11 publications

(13 citation statements)

References 9 publications

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“…The counts of Enterobacteriaceae were reduced in the cecal content of HSD+FPLS compared to that of LSD and HSD chicks. Regardless of the effect of stocking density, the antibacterial activity of papaya seed (Sugiharto, 2020) and leaves (Lonkala & Reddy, 2019) in FPLS may be responsible for the reduced Enterobacteriaceae population in the cecum of ICC in the present study. Indeed, the fermented feed component itself may also lead to the reduced count of Enterobacteriaceae in the cecal content of ICC, as was previously indicated by Olukomaiya et al (2019) in broiler chickens.…”

Section: Selected Bacterial Counts and Intestinal Morphology Of Iccmentioning

confidence: 58%

Performances of Crossbred Chickens Fed Fermented Papaya Leaf and Seed Powder at High Stocking Density

Sugiharto

Yudiarti

Widiastuti

et al. 2021

Trop. Anim. Sci. J.

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The study evaluated the influence of fermented papaya leaf and seed powder (FPLS) and/or multienzymes on the growth, physiology, antioxidant, and gut ecology of the Indonesian crossbred chicken (ICC) at high stocking density. Three hundred and seventy ICC were randomly allotted to LSD (chicks fed conventional feed at low stocking density), HSD (chicks fed conventional feed at high stocking density), HSD+mE (chicks fed conventional feed plus multienzyme at high stocking density), HSD+FPLS (chicks fed FPLS at high stocking density) and HSD+FPLS+mE (chicks fed FPLS plus multienzyme at high stocking density). Body weight and feed intake were determined weekly. Two ICC were taken from each pen ( 10chicks per treatment group) at week 10 for sampling. The study was arranged based on a completely randomized design with five treatment groups, each consisted of five replicates. Except for performance, analysis of variance was conducted on two chicks from each replicate (10 chicks per treatment group). Chicks in LSD consumed more (p<0.05) feed and had a higher (p<0.05) feed conversion ratio. Platelet distribution width (PDW) was lower (p<0.05) in HSD, HSD+FPLS, and HSD+FPLS+mE chicks than in LSD chicks. Lymphocyte counts were lower (p<0.05) in HSD relative to HSD+mE chicks. Superoxide dismutase (SOD) was higher (p<0.05) in HSD and HSD+FPLS+mE chicks than in LSD, HSD+mE, and HSD+FPLS chicks. High-density lipoprotein was smaller (p<0.05) in HSD+mE chicks than in LSD, HSD, and HSD+FPLS chicks. Compared to the other treatment groups of chicks, HSD+FPLS chicks had a lower (p<0.05) albumin level. Creatinine level was lower (p<0.05) in HSD chicks than in the other group of chicks. Enterobacteriaceae counts were lower (p<0.05) in HSD+FPLS cecal content of chicks than in LSD and HSD chicks. The redness values of breast meats were lower (p<0.05) in HSD+FPLS chicks than the chicks in HSD+mE and HSD+FPLS+mE dietary treatments. LSD chicks had higher (p<0.05) redness values of thigh meat than the other treatment groups of chicks. LSD chicks also had higher (p<0.05) yellowness values than HSD+mE and HSD+FPLS+mE chicks. In conclusion, high stocking density resulted in mild stress conditions, as was demonstrated by the increased SOD and decreased PDW and redness meat values. A combination of FPLS and multienzyme ameliorated the adverse influence of high stocking density in ICC.

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Section: Selected Bacterial Counts and Intestinal Morphology Of Iccmentioning

confidence: 58%

Performances of Crossbred Chickens Fed Fermented Papaya Leaf and Seed Powder at High Stocking Density

Sugiharto

Yudiarti

Widiastuti

et al. 2021

Trop. Anim. Sci. J.

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“…Herbal-based traditional medicines have always been a part of human culture since the ancient time [ 1 ]. In the modern era, medicinal plants are considered as the center of attention for enormous investigation of their inherent biological effect [ 2 ].…”

Section: Introductionmentioning

confidence: 99%

“…In the modern era, medicinal plants are considered as the center of attention for enormous investigation of their inherent biological effect [ 2 ]. Screening of natural plants, targeting specific therapeutic activity, has led to the revelation and discovery of clinically effective medicine to cope with life-threatening human disease [ 1 – 4 ]. In Ayurveda, the use of herbal extracts and nutritional supplements for the treatment of infectious diseases as an alternative or complementary medicine has been well documented and preserved for about 5,000 years.…”

Section: Introductionmentioning

confidence: 99%

Study of Antibacterial Activity of Root Bark, Leaves, and Pericarp Extracts of Diploknema butyracea and Evaluation of Prospective Antioxidant Activity

Chhetry

Dhakal

Chaudhary

et al. 2022

Journal of Tropical Medicine

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This study was aimed to determine the antibacterial activity of root bark, leaves, and pericarp extract of Diploknema butyracea and to evaluate the prospective antioxidant activity, total flavonoid, polyphenol, and carbohydrate content. The plant parts were collected and extracted by cold maceration, using hexane, ethyl acetate, methanol, and distilled water. Phytochemical screening of different samples of D. butyracea in different solvents revealed the presence of varied extent of alkaloid, saponin, terpenoid, anthraquinones, tannin, cardiac glycoside, flavonoid, carbohydrate, polyphenol, protein and amino acid, resin, and phytosterol. Our study showed that methanolic root bark extract exhibited the potent antimicrobial activity against Staphylococcus aureus, Staphylococcus epidermidis, and Klebsiella pneumonia with an average zone of inhibition of 17.33 mm, 14.33 mm, and 13.0 mm, respectively. Surprisingly, all of the extracts were insensitive to Escherichia coli. The lowest minimum bactericidal concentration (MBC), 4.6 mg/ml, was observed with the aqueous pericarp extract against S. epidermidis and the highest was of 50 mg/ml shown by ethyl acetate pericarp against K. pneumonia. Our results showed that both the polar and nonpolar components present in the different parts of D. butyracea exhibit prominent antibacterial activities against different bacterial strains. The in vitro 2,2′-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging activity showed that the methanol extract of root barks displayed the most potent antioxidant activity (IC50 : 6.1 µg/ml). The total polyphenol content of the plant part extracts was observed between 19.48 ± 0.23 and 123.48 ± 1.84 µg gallic acid equivalent/mg of dry extract weight. Likewise, flavonoid content ranged from 40.63 ± 1.28 µg to 889.72 ± 3.40 μg quercetin equivalent/mg of dry extract weight and total carbohydrate content ranged from 11.92 ± 0.60 µg to 174.72 ± 0.60 µg glucose equivalent per/mg dry extract weight. Overall, our study showed that the root bark, pericarp, and leaves extract of D. butyracea evinced prominent antibacterial properties against various pathogenic bacterial strains.

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“…Indeed, some of these plants have been reported worldwide to be used in the treatment of many diseases (Kengni et al, 2014: Yemele et al, 2015. Relatively to bacterial infection, the antibacterial activity of many of the above mentioned plants has been proved (Sospeter et al, 2015 ;Kengni et al, 2014;Amit, 2017 ;Amado et al, 2019 ;Srividya et Rama, 2019).…”

Section: Discussionmentioning

confidence: 99%

Contribution to the ethnobotanical inventory of medicinal plants used for the treatment of typhoid fever in Adamaoua region, Cameroon

Mefokou¹,

Tangue²,

Sokoudjou³

et al. 2021

Int. J. Bio. Chem. Sci

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Since ancient Greek-Roman times, the use of plants to cure many human diseases is still common. The present ethnobotanical survey was conducted to contribute to the knowledge of medicinal plants used for the treatment of typhoid fever in three sub divisions of Vina division, Adamawa Cameroon. After having explained the importance of this study to interviewees, 41 traditional healers have agreed and delivered information regarding the medicinal plants they use as well as the different preparation and administration through a well- structured questionnaire that was given to them on this matter. Among 41 traditional healers whose attended this study, 32 were men and 09 were women. The ethnobotanical survey allowed the identification of 70 plants belonging to 38 families. With a frequency of 11/70, the Fabaceae family was the most represented followed by that of Rubiaceae and Asteraceae (04/70 each). The leaves are the most used parts (34.28%) followed by leaves + roots (14.28%) and the whole plant (12.86%). The majority of the recipes consisted of four to six plants (34.66), and were prepared by decoction (50%), with water as the main solvent (87.80%). 41.56% of typhoid preparations are administered twice daily for a duration of 14 days (46.77%). This is the first report on antityphoid herbal remedies in Vina division-Adamawa Cameroon. It would therefore be judicious for our government and research institution to investigate on their therapeutic properties in order to develop ameliorated and efficient phytomedicines.

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Antibacterial Activity of Carica papaya Leaves and Allium sativum Cloves Alone and in Combination against Multiple Strains

Cited by 11 publications

References 9 publications

Performances of Crossbred Chickens Fed Fermented Papaya Leaf and Seed Powder at High Stocking Density

Performances of Crossbred Chickens Fed Fermented Papaya Leaf and Seed Powder at High Stocking Density

Study of Antibacterial Activity of Root Bark, Leaves, and Pericarp Extracts of Diploknema butyracea and Evaluation of Prospective Antioxidant Activity

Contribution to the ethnobotanical inventory of medicinal plants used for the treatment of typhoid fever in Adamaoua region, Cameroon

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