Antibacterial activity, cytotoxicity and mechanical behavior of nano-enhanced denture base resin with different kinds of inorganic antibacterial agents

Chen, Rongrong; Han, Zhiwu; Huang, Zhuoli; Karki, Junu; Wang, Chenxin; Zhu, Bangshang; Zhang, Xiu Yin

doi:10.4012/dmj.2016-301

Cited by 86 publications

(77 citation statements)

References 39 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…[ 186 ] In dentistry, TiO 2 nanoparticles have been mixed with commercial and noncommercial dental resins to produce tooth filling materials with antimicrobial properties and improved mechanical strength. [ 187,188 ] As a wide‐bandgap semiconductor, TiO 2 nanoparticles have been incorporated into antibacterial paints or coatings for hospital touch‐surfaces where their antibacterial activity may be activated by excitation with visible light. [ 189 ] Excitation of TiO 2 nanoparticles by ultraviolet light produces ROS that can destroy many organic molecules.…”

Section: Metal‐based Nanocompoundsmentioning

confidence: 99%

Metal‐Based Nanomaterials in Biomedical Applications: Antimicrobial Activity and Cytotoxicity Aspects

Makvandi

Wang

Zare

et al. 2020

Adv Funct Materials

478

368

View full text Add to dashboard Cite

Microbial colonization on material surfaces is ubiquitous. Biofilms derived from surface-colonized microbes pose serious problems to the society from both an economical perspective and a health concern. Incorporation of antimicrobial nanocompounds within or on the surface of materials, or by coatings, to prevent microbial adhesion or kill the microorganisms after their attachment to biofilms, represents an important strategy in an increasingly challenging field. Over the last decade, many studies have been devoted to preparing meta-based nanomaterials that possess antibacterial, antiviral, and antifungal activities to combat pathogen-related diseases. Herein, an overview on the state-of-the-art antimicrobial nanosized metal-based compounds is provided, including metal and metal oxide nanoparticles as well as transition metal nanosheets. The antimicrobial mechanism of these nanostructures and their biomedical applications such as catheters, implants, medical delivery systems, tissue engineering, and dentistry are discussed. Their properties as well as potential caveats such as cytotoxicity, diminishing efficacy, and induction of antimicrobial resistance of materials incorporating these nanostructures are reviewed to provide a backdrop for future research.

show abstract

Section: Metal‐based Nanocompoundsmentioning

confidence: 99%

Metal‐Based Nanomaterials in Biomedical Applications: Antimicrobial Activity and Cytotoxicity Aspects

Makvandi

Wang

Zare

et al. 2020

Adv Funct Materials

478

368

View full text Add to dashboard Cite

show abstract

“…30,31 It has been reported that composite resin containing zirconium oxide particles and aluminum borate whisker showed higher antibacterial activity. 32 In this study, antibacterial activity was not evaluated, but it is necessary to conduct further studies to investigate the antibacterial effects of different contents of materials. The surface roughness of restorative materials has a major effect on the discoloration and initial bacterial adhesion.…”

Section: Discussionmentioning

confidence: 99%

The effect of ionizing radiation on properties of fluoride-releasing restorative materials

2020

View full text Add to dashboard Cite

The purpose of this study was to evaluate the effect of ionizing radiation from high energy X-ray on fluoride release, surface roughness, flexural strength, and surface chemical composition of the materials. The study groups comprised five different restorative materials: Beautifil II, GCP Glass Fill, Amalgomer CR, Zirconomer, and Fuji IX GP. Twenty disk-shaped specimens (8x2 mm) for fluoride release and 20 bar-shaped specimens (25 x 2x 2 mm) for flexural strength were prepared from each material. Each material group was divided into two subgroups: irradiated (IR) and non-irradiated (Non-IR). The specimens from IR groups were irradiated with 1.8 Gy/day for 39 days (total IR = 70.2 Gy). The amount of fluoride released into deionized water was measured using a fluoride ion-selective electrode and ion analyzer after 24 hours and on days 2, 3, 7, 15, 21, 28, 35, and 39 (n = 10). The flexural strength was evaluated using the three-point bending test (n = 10). After the period of measurement of fluoride release, seven specimens (n = 7) from each group were randomly selected to evaluate surface roughness using AFM and one specimen was randomly selected for the SEM and EDS analyses. Data were analyzed with two-way ANOVA and Tukey tests (p = 0.05). The irradiation significantly increased fluoride release and surface roughness for Amalgomer CR and Zirconomer groups (p < 0.05). No significant change in flexural strength of the materials was observed after irradiation (p > 0.05). The ionizing radiation altered the amount of fluoride release and surface roughness of only Amalgomer CR and Zirconomer. The effect could be related to the chemical compositions of materials.

show abstract

“…Another study reported that the use of 3% of TiO 2 resulted in antibacterial activity without comprising the mechanical properties and cytotoxicity of PMMA [21]. Another research on the addition of TiO 2 into PMMA showed that the incorporation of nano-sized TiO 2 adversely affected the mechanical properties and the flexural strength values with increase in TiO 2 concentration [33].…”

Section: Discussionmentioning

confidence: 99%

“…Chen et al ., 2017 revealed that the use of nano-sized 3% TiO 2 had antibacterial activities compared to the control and blank groups with no significant differences in the cytotoxicity and found no significant differences in the mechanical properties compared to the control group within the range of an appropriate ratio [21]. The different percentages of superinducing TiO 2 nanofiller 1% and 5% were added to the acrylic which showed that 5% of TiO 2 nanoparticles can adversely affect its flexural strength [22].…”

Section: Introductionmentioning

confidence: 99%

TiO2-Nanofillers Effects on Some Properties of Highly- Impact Resin Using Different Processing Techniques

Aziz¹

2018

TODENTJ

View full text Add to dashboard Cite

Background:The criteria of conventional curing of polymethyl methacrylate do not match the standard properties of the denture base materials.Objectives:This research was conducted to investigate the addition of TiO2 nano practical on impact strength, thermal conductivity and color stability of acrylic resin cured by microwave in comparison to the conventional cured of heat-polymerized acrylic resin.Materials and Methods:120 specimens made of high impact acrylic resin were divided into two main groups according to the type of curing (water bath, microwave), then each group was subdivided into two groups according to the addition of 3% TiO2 nano-fillers and control group (without the addition of TiO2 0%). Each group was subdivided according to the type of test into 3 groups with 10 specimens for each group. Data were statistically analyzed using Student t-test to detect the significant differences between tested and control groups at significance level (P<0.05).Results:According to curing type methods, the results showed that there was a significant decrease in impact strength of microwaved cured resin, but there was no significant difference in the thermal conductivity and color stability of resin. In addition, by using nanofiller, there was a significant increase in the impact strength and color stability with the addition of 3% TiO2 nanofillers, but no significant difference was found in the thermal conductivity of the acrylic resin.Conclusion:The microwave curing of acrylic resin had no change in the color stability and thermal conductivity in comparison to the water bath, but the impact strength was decreased. The addition of 3% TiO2 improved the impact and the color stability, but the thermal conductivity did not change.

show abstract

Antibacterial activity, cytotoxicity and mechanical behavior of nano-enhanced denture base resin with different kinds of inorganic antibacterial agents

Cited by 86 publications

References 39 publications

Metal‐Based Nanomaterials in Biomedical Applications: Antimicrobial Activity and Cytotoxicity Aspects

Metal‐Based Nanomaterials in Biomedical Applications: Antimicrobial Activity and Cytotoxicity Aspects

The effect of ionizing radiation on properties of fluoride-releasing restorative materials

TiO2-Nanofillers Effects on Some Properties of Highly- Impact Resin Using Different Processing Techniques

Contact Info

Product

Resources

About