Anti-Obesity and Hypolipidemic Effects of Black Soybean Anthocyanins

Abstract

The effect of anthocyanins extracted from black soybean (Glycine max L.) seed coats on body weight, adipose tissue weight, and serum lipids was evaluated in rats fed a high fat diet (HFD). Rats were raised on a normal diet (ND) (based on the AIN-93M diet), HFD (ND supplemented with 16% lard oil), HFD containing 10% black soybean, and HFD containing 0.037% black soybean anthocyanins (equivalent to that in the 10% black soybean diet). Weight gain was significantly lowered in the rats fed HFD plus black soybean anthocyanins compared with the rats fed HFD alone (P < .05) and reversed to the level of the rats fed ND. The black soybean diet also decreased body weight gain compared with the HFD (P < .05). The black soybean anthocyanins-added diet suppressed the HFD-induced weight gain in liver intermediately and tended to decrease the weights of epididymal and perirenal fat pads. The black soybean anthocyanins were also effective in improving the lipid profile. They significantly reduced the levels of serum triglyceride and cholesterol (P < .05), while they markedly increased the high-density lipoprotein-cholesterol concentration, which was decreased in the rats fed HFD (P < .05). These results indicate that the anthocyanins in black soybean seed coats have an anti-obesity effect, which can reverse the effects of HFD on body weight, adipose tissue weight, and serum lipid contents.

Effect of processing method on nutritional quality of black soybean

“…Bhatt is traditionally prepared in an iron kadhai to make chudkani, bhatwani and thatwani. The anthocyanins in black soybean seed coat have anti-obesity effect (Kwon et al, 2007). Earlier reports have indicated that by various treatments nutritional quality of legume can be changed to increase its nutrient utilization efficiency (Jood et al,1986, Mubarak,2005Sharma et al, 2011;Odiba, 2011).…”

Effects of jaboticaba (Myrciaria jaboticaba) peel on blood glucose and cholesterol levels in healthy rats

“…Kwon et al evaluated the effect of black soy anthocyanins addition on an hyperlipidic diet of rats and observed 23 and 20% reduction in triglycerides and cholesterol levels, respectively, and an increase of 37% in the HDL-cholesterol fraction (Kwon, et al, 2007). In contrast to the present, a recent study showed that FJP could enhance HDL-cholesterol in obese rats (Lenquiste et al, 2012).…”

Jaboticaba (Myrciaria jaboticaba (Vell.) Berg.) peel improved triglycerides excretion and hepatic lipid peroxidation in high-fat-fed rats

“…The impact of anthocyanins on the serum lipids of rats fed high-fat diets is controversial 7,10,21 . Kwon et al 7 found that SD rats fed 10% black soybean or 0.037% anthocyanin extract presented lower total serum cholesterol and triglyceride levels.…”

“…Kwon et al 7 found that SD rats fed 10% black soybean or 0.037% anthocyanin extract presented lower total serum cholesterol and triglyceride levels. However, studies with obese mice treated with a high-anthocyanin beverage or diet corroborate our findings 10,21 .…”

“…These diets may reduce total serum cholesterol and triglyceride levels 7 and increase High Density Lipoproteincholesterol (HDL-cholesterol) levels in obese animals 6 . The mechanism underlying these findings may regard the ability of these diets to increase biliary cholesterol excretion and fecal lipid excretion, reducing plasma lipid levels 5 .…”