Anti–inflammatory activity of the glandular extracts of Thunnus alalunga

Azeem, A. K.; Dilip, C; S.M.Prasanth,; Shahima, V Junise Hanan; Sajeev, Kumsr; Naseera, C.

doi:10.1016/s1995-7645(10)60190-3

Cited by 56 publications

(41 citation statements)

References 3 publications

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“…prostaglandin E2 (PGE2), prostaglandin D2 (PGD2), prostacycline (PGI2) and thromboxane A2 (TxA2). Eicosanoids are derived from polyunsaturated fatty acid arachidonic acid (AA; 20:4, n-6) by action of COX-1 and COX-2 [14][15][16][17][18][19][20] . PGE2 depresses the humoral antibody response by inhibiting the differentiation of B-lymphocytes into antibody secreting plasma cells.…”

Section: Discussionmentioning

confidence: 99%

Antiarthritic effects of Ajuga bracteosa Wall ex Benth. in acute and chronic models of arthritis in albino rats

Kaithwas

Gautam

Jachak

et al. 2012

Asian Pacific Journal of Tropical Biomedicine

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Section: Discussionmentioning

confidence: 99%

Antiarthritic effects of Ajuga bracteosa Wall ex Benth. in acute and chronic models of arthritis in albino rats

Kaithwas

Gautam

Jachak

et al. 2012

Asian Pacific Journal of Tropical Biomedicine

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“…Lysosomal enzymes released during inflammation produce a variety of disorders. In vitro anti-inflammation activities of glandular extracts of albacore tuna (Thunnus alalunga) by HRBC assay (Azeem et al, 2010) and that of the digested peptides derived from Chum salmon (Oncorhynchus keta) in RAW 264.7 macrophage cells by WST-1 assay (Saigusa, Nishizawa, Shimizu, & Saeki, 2015) have been reported.…”

Section: Introductionmentioning

confidence: 99%

Untitled

Kumar¹,

Shakila²,

Jeyasekaran³

2019

Turk. J. Fish. Aquat. Sci.

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In this study, skin of unicorn leatherjacket (Aluterus monoceros) was hydrolyzed using collagenase at three different temperatures viz. 5°C, 25°C and 50°C, to obtain collagen hydrolysates. Collagen peptides of low molecular masses (<3kDa) viz. CP-5, CP-25 and CP-50 were obtained by sequential ultrafiltration with tangential flow filtration (TFF) system. The results indicated that CP-5 exhibited the maximum in vitro anti-cancer, anti-diabetic and wound healing activities than CP-25 and CP-50. In MTT assay, CP-5 inhibited the viability of COLO320 cancer cells upto 49.78% at 1 mg/mL concentration, while the inhibition was only 29.92% by CP-50. Anti-diabetic activity as assessed by α-amylase inhibition was 80.45% by CP-5 at 1 mg/mL concentration, as against 75.81% and 71.17% by CP-25 and CP-50, respectively. Collagen peptides, in general, exhibited very low anti-inflammatory property, which ranged between 3.27% to 4.01%. In vitro wound healing tested by scratch assay showed good migration of 3T3-L1 cells in CP-5 treated than CP-25 and CP-50 at 0.2 mg/mL concentration. The study thus proved that collagen peptides derived from fish skin at low hydrolysis temperatures (50C) exhibited more bio-active activities than those hydrolysed at high temperatures (500C); and shall be effectively utilized in various bio-medical applications.

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“…Conversely, it may be inappropriate, altered homeostasis, pathologic and damaging when it is reacting out of proportion causing undesired effects (Miller et al 2009;Abdelmagid et al 2015) and contribute to diseases. In fact, inflammation is implicated in osteoarthritis, heart disease, Alzheimer's, age-related macular degeneration, chronic obstructive pulmonary disease, multiple sclerosis, stroke and cancer (McCarty 1999;Azeem et al 2010;Medzhitov 2010;Kumar et al 2011). Inflammation is frequently associated with the increase in vascular permeability and mediator release (Vane & Botting 1998), increase of protein denaturation and membrane alteration (Umapathy et al 2010).…”

Section: Introductionmentioning

confidence: 99%

Phytochemical screening and anti-inflammatory properties of AlgerianHertia cheirifoliamethanol extract

Bouriche

Kada

Assaf

et al. 2016

Pharmaceutical Biology

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Context: Hertia cheirifolia L. (Asteraceae) is traditionally used in Northern Africa to treat various inflammatory infections. However, few studies on this plant have been reported. Objective: The anti-inflammatory activity of methanol extract of H. cheirifolia leaves was investigated using different experimental models. Materials and methods: Phytochemical analysis was performed to determine phenolic compounds. Acute toxicity of the extract (2000 mg/kg) was examined in Swiss albino mice for 14 days, before croton oilinduced ear oedema in mice, carrageenan-induced paw oedema in Swiss albino rats, cotton pellet-induced granuloma in rats and carrageenan-induced air pouch in mice were conducted. The IL-1b and TNF-a release from concanavalin A-stimulated monocytes was measured by ELISA. Results: Methanol extract of H. cheirifolia is rich in polyphenols and flavonoids. Cinnamic acid and rutin represent the major constituents. Methanol extract up to 2000 mg/kg did not produce any toxic effects. Topical application of 2 mg/ear of the extract produced 78.7% of inhibition on ear swilling. Oral pre-treatment of rats with 200 and 400 mg/kg of the extract inhibited paw oedema by 70% and 89%, respectively. At 200 mg/kg, granuloma dry and wet weights were reduced by 41.85% and 61.72%, respectively. Moreover, the treatment with methanol extract at 1 mg/kg exerted 62.7% of inhibition on leucocytes migrated into the ear pouch. TNF-a and IL-1b release was reduced by 69% and 78%, respectively, with 1 lg/mL of the extract. Conclusion: Methanol extract of H. cheirifolia possesses a strong anti-inflammatory activity and may be considered an interesting source of effective anti-inflammatory compounds.ARTICLE HISTORY

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Anti–inflammatory activity of the glandular extracts of Thunnus alalunga

Cited by 56 publications

References 3 publications

Antiarthritic effects of Ajuga bracteosa Wall ex Benth. in acute and chronic models of arthritis in albino rats

Antiarthritic effects of Ajuga bracteosa Wall ex Benth. in acute and chronic models of arthritis in albino rats

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Phytochemical screening and anti-inflammatory properties of AlgerianHertia cheirifoliamethanol extract

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