volume 29, issue 3, P659-676 2012
DOI: 10.3233/jad-2012-111709
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Gui Hua Lin, Young-Jung Lee, Dong-Young Choi, Sang Bae Han, Jae Kyung Jung, Bang Yeon Hwang, Dong Cheul Moon, Youngsoo Kim, Myung Koo Lee, Ki-Wan Oh, Heon Sang Jeong, Jae Yoon Leem, Hwa Kyoung Shin, Jung Hwa Lee et al.

Abstract: Neuroinflammation is implicated for amyloidogenesis. Sulfur compounds extracted from garlic have been shown to have anti-inflammatory properties. Previously, we have investigated that thiacremonone, a sulfur compound isolated from garlic has anti-inflammatory effects. To investigate thiacremonone's potential effect on anti-neuroinflammation and anti-amyloidogenesis, 4 week old ICR mice were given different doses of thiacremonone (1, 3, and 10 mg/kg) in drinking water for 1 month and received intraperitoneal in…

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