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Cited by 12 publications
(11 citation statements)
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References 8 publications
(11 reference statements)
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“…Nonetheless, several epidemiological studies suggest that some of the plant-derived molecules described here may reduce human mortality and chronic diseases in humans. For instance, individuals who regularly consume coffee—arguably the highest source of polyphenols and caffeine in the human diet—live longer and show a reduced incidence of cancer, cardiovascular disease and Alzheimer's disease compared with non-consumers [ 41 , 42 ]. Similarly, people who regularly take metformin [ 43 ] or glucosamine [ 44 , 45 ], as well as those who have a higher dietary intake of spermidine [ 46 ], live longer than non-users or controls.…”
Section: Challenges and Opportunitiesmentioning
confidence: 99%
“…Nonetheless, several epidemiological studies suggest that some of the plant-derived molecules described here may reduce human mortality and chronic diseases in humans. For instance, individuals who regularly consume coffee—arguably the highest source of polyphenols and caffeine in the human diet—live longer and show a reduced incidence of cancer, cardiovascular disease and Alzheimer's disease compared with non-consumers [ 41 , 42 ]. Similarly, people who regularly take metformin [ 43 ] or glucosamine [ 44 , 45 ], as well as those who have a higher dietary intake of spermidine [ 46 ], live longer than non-users or controls.…”
Section: Challenges and Opportunitiesmentioning
confidence: 99%
“…There are a number of studies showing that consumption of coffee is linked to a lower risk of various types of cancer, type 2 diabetes, ischemic stroke, Alzheimer’s disease and Parkinson’s disease. As shown by the latest research, coffee not only improves concentration and motor skills; it also has antiaging properties [ 17 , 18 ]. It must be stressed, however, that beside many beneficial properties mentioned in this article coffee may also have harmful effects during excessive intake.…”
Section: Introductionmentioning
confidence: 99%
“…Probably the most striking effect of coffee intake is the ability to increase lifespan and, most importantly, healthspan on ageing [ 106 , 150 , 151 , 152 , 153 , 154 , 155 , 156 , 157 ], as concluded from the analysis of different cohorts in Europe [ 158 , 159 , 160 , 161 , 162 , 163 , 164 ], America [ 165 , 166 , 167 ], and Asia [ 168 , 169 , 170 , 171 ], with different ethnicities [ 170 ] and different types of coffee [ 167 ]; these effects were observed similarly in both men and women [ 152 , 161 ] with different polymorphisms [ 162 , 172 ], sharply contrasting with the positive association of life-long acrylamide exposure [ 173 ] and acrylamide–hemoglobin adducts [ 174 ] with mortality.…”
Section: Other General Beneficial Health Effects Of Coffeementioning
confidence: 99%