Anti-acne activity of &lt;i&gt;Casuarina equisetifolia&lt;/i&gt; bark extract: A randomized clinical trial

Shafiq, Yousra; Naqvi, Baqir Shyum; Rizwani, Ghazala H.; Usman, Muhammed; Shah, Barkat Ali; Aslam, Muhammad; Hina, Bushra

doi:10.3329/bjp.v9i3.19342

Cited by 11 publications

(8 citation statements)

References 15 publications

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“…Based on full‐text review, 12 reports failed to meet the inclusion criteria (see Fig. ), resulting in 26 studies that met the criteria for final analysis …”

Section: Resultsmentioning

confidence: 99%

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Use of the hCONSORT criteria as a reporting standard for herbal interventions for common dermatoses: a systematic review

Ornelas

Routt

Kallis

et al. 2018

British Journal of Dermatology

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“…Based on full‐text review, 12 reports failed to meet the inclusion criteria (see Fig. ), resulting in 26 studies that met the criteria for final analysis …”

Section: Resultsmentioning

confidence: 99%

“…Only four of 26 studies reported at least 50% of information recommended in the hCONSORT guidelines . None of the studies fulfilled at least one criterion in each category.…”

Section: Resultsmentioning

confidence: 99%

Use of the hCONSORT criteria as a reporting standard for herbal interventions for common dermatoses: a systematic review

Ornelas

Routt

Kallis

et al. 2018

British Journal of Dermatology

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“…Many plants have recently be reported with anticancer activity like Casuarina equisetifolia (Shafiq et al, 2014), Aspergillus niger (Channabasavaet al, 2014) and Convolvulus arvensis (Saleem et al, 2014).…”

Section: Introductionmentioning

confidence: 99%

Anticancer activity of <i>Morus nigra</i> leaves extract

Qadir

Ali

Ibrahim

2014

Bangladesh J Pharmacol

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Plants are screened for treatment of many ailments including cancer because they possess certain potential constituents which are effective for treatment. The aim of this study was to evaluate the anti-cancer activity of Morus nigra leaves against human cervical cancer cell line (HeLa). n-Hexane and aqueous methanolic extract of plant's leaves were made by maceration. Anti-cancer activity was estimated by methyl-thiazolyl-tetrazolium (MTT) assay and percentage inhibition of cells was calculated. Results of MTT showed that 100 µg/mL aqueous methanol extract of M. nigra inhibited 89.5 -32.0% of HeLa cell line. It was concluded that M. nigra possess anti-cancer activity. Article Info

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“…Terpenoids have the ability to quench the singlet oxygen and to transfer hydrogen or electron that proves it to be a potential antioxidant [45].…”

Section: Total Antioxidant Capacity Assaymentioning

confidence: 99%

Phytochemical Analysis and in Vitro Studies on Antibacterial, Antioxidant and Anti-Inflammatory Activities Using Casuarina Equisetifolia Bark Extracts

Saranya¹,

Gowrie²

2018

Int J Pharm Pharm Sci

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Objective: Casuarina equisetifolia is an important multipurpose exotic forest tree species widely cultivated in the coastal regions of Tamil Nadu that serves as a warehouse of essential secondary metabolites. Identification of these bioactive compounds in this forest tree species might lead to the discovery and development of a new drug to treat various diseases. Methods:The present study was carried out with an objective to analyse the phytochemicals qualitatively and quantitatively. Gas ChromatographyMass Spectrometry (GC-MS) analysis was performed to evaluate the presence of various volatile compounds. An in vitro antibacterial, antioxidant and anti-inflammatory properties of aqueous and organic solvents of C. equisetifolia bark was studied. Results:The preliminary qualitative screening revealed the presence of alkaloids, glycosides, carbohydrates, proteins, flavonoids, phenols, terpenoids, and tannins. The quantitative analysis revealed the presence of maximum phenols (71.2±0.51 mg/g), flavonoids (35.12±0.34 mg/g), tannins (77.59±0.21) and terpenoids (6%) in methanolic root extract with respective standards. Several peaks were obtained in the GC-MS analysis which indicates the presence of different secondary metabolites. Antibacterial activity showed a maximum zone of inhibition against Escherichia coli (23±0.24 mm) and Proteus vulgaris (23±0.32 mm). The antioxidant potential of various extracts was compared with the standard ascorbic acid. Anti-inflammatory activity was compared with standard diclofenac sodium and the extract showed activities significantly in a dose-dependent manner. Conclusion:From this study, it is revealed that C. equisetifolia bark extract possesses efficient antibacterial property, the potential in scavenging free radical, effective antioxidant, powerful anti-inflammatory source that can be employed in the development of a novel drug to treat various diseases.

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Anti-acne activity of <i>Casuarina equisetifolia</i> bark extract: A randomized clinical trial

Cited by 11 publications

References 15 publications

Use of the hCONSORT criteria as a reporting standard for herbal interventions for common dermatoses: a systematic review

Use of the hCONSORT criteria as a reporting standard for herbal interventions for common dermatoses: a systematic review

Anticancer activity of <i>Morus nigra</i> leaves extract

Phytochemical Analysis and in Vitro Studies on Antibacterial, Antioxidant and Anti-Inflammatory Activities Using Casuarina Equisetifolia Bark Extracts

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