Anthropometrical parameters and markers of obesity in rats

Abstract

SummaryThe present study was undertaken to determine anthropometrical parameters in male adult Wistar rats. We tested the hypothesis that the anthropometrical index may identify obesity and may predict its adverse effects on lipid profile and oxidative stress in rats. Two experimental protocols were performed. In the first experiment, 50 male Wistar rats, 21 days old and fed a control chow were studied up to 150 days of age. In the second experiment, male Wistar rats, 60 days old, were divided into three groups (n ¼ 8): control (C) given free access to a control chow; (S) receiving the control chow and drinking 30% sucrose ad libitum and (HC) fed a high-carbohydrate diet ad libitum. The first experiment showed that food consumption, energy intake and body weight increased with increasing age, while specific rate of body mass gain was significantly decreased. There were no significant differences in body length and thoracic circumference of rats from 60 days of age. The abdominal circumference (AC) and body mass index (BMI) significantly increased with enhancing age in rats up to 90 days of age and remained constant thereafter. In the second experiment, after 30 days of dietary treatment, the final body weight, body mass gain, carcass fat and BMI were higher in S and HC rats than in C. There were no significant alterations in body length and carcass protein among the groups. Triacylglycerol (TG), total cholesterol (CT), low-density lipoprotein cholesterol (LDL-C) and lipid hydroperoxide (LH) were higher in S and HC rats than in C. High-density lipoprotein cholesterol (HDL-C) decreased in HC rats and total antioxidant substances (TAS) decreased in S and HC rats. There were positive correlations between BMI with carcass fat, BMI with LH and BMI and serum TG concentration. In conclusion, the BMI for male adult Wistar rats ranged between 0.45 and 0.68 g/cm 2 . Obesity may be easily estimated from the BMI in rats. Alterations in BMI were associated with dyslipidemic profile and oxidative stress in serum of rats and BMI may predict these adverse consequences of the obesity in rats.

Suplementação Com Amêndoa De Bacuri Na Composição Corporal De Ratos Submetidos Ao Exercício

“…Porém, no presente estudo, todos os grupos iniciaram o protocolo de treinamento e suplementação proteica com valores próximos a 0,6 aumentando para 0,8. Para Angéloco et al 28 , o IMC pode estimar de forma confiável a gordura corporal em rato, sendo diretamente proporcional ao seu crescimento, já o índice de Lee é considerado menos sensível, pois animais com elevada quantidade de massa muscular podem apresentar elevado índice de Lee mesmo que a gordura corporal não seja excessiva [19][20][21] .…”

“…No entanto, nessa pesquisa os resultados não evidenciaram grandes diferenças nesses parâmetros e não refletiram alterações substanciais da gordura total entre os grupos avaliados. Pesquisa realizada com ratos mostrou que valores de IMC aumentaram até 90 dias de idade (0,45 para 0,68 g/cm 2 ), mantendo-se constantes até 150 dias 19 . No presente trabalho, os valores variaram entre 0,30 a 0,40 g/cm 2 (idade de 43 dias) e após oito semanas de treinamento anaeróbico resistido em escadas (idade de100 dias) variaram de 0,57 a 0,65 g/cm 2 , estando, portanto, dentro dos parâmetros de normalidade para ratos Wistar.…”

“…O Índice de Lee foi calculado pela relação entre a raiz quadrada de peso corporal (g) e o comprimento (cm) e o Índice de Massa Corporal (IMC) pela razão entre peso corporal (g) e comprimento 2 (cm) 19 . O índice de adiposidade (IA%) foi calculado através da relação entre a gordura corporal total e o peso corporal final multiplicado por 100 20 .…”

Changes in body composition and mRNA expression of ghrelin and lipoprotein lipase in rats treated with leuprolide acetate, a GnRH agonist

“…All measures were determined according to equations described by Novelli et al (14), where the specific rate of body mass gain is defined as follows: Body mass gain (g/kg)=dM/Mdt, where dM represents the gain of body weight during dt=t2-t1 and M is the rat body weight at the time-point t1.…”

Effect of Trigonella Foenum-Graecum seed powder on anthropometrical and nutritional parameter

“…Body mass index (BMI) = body weight (g) / length 2 (cm 2 ) (Novelli et al, 2007) Specific rate of body mass gain (g/kg) = dM / M dt, where dM represents the gain of body weight during dt = t 2 -t 1 and M is the rat body weight at t 1 (Novelli et al, 2007) Based on food and caloric intake (Diniz et al 2005), the following nutritional parameters were calculated: Energy intake (kJ/day) = mean food consumption x dietary metabolizable energy (Novelli et al, 2007) Feed efficiency (FE; g gained/kcal) = (mean body weight gain (g) 100) / total energy intake (kcal) (Cope et al, 2007) …”