1988
DOI: 10.1001/archderm.124.4.548
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Anthralin-corticosteroid combination therapy in the treatment of chronic plaque psoriasis

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Cited by 9 publications
(6 citation statements)
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“…The last study mentioned used a maximum concentration of anthralin that was 2 to 16 times less than the maximum concentration used in other studies. [12][13][14]17,18,26,40 Moreover, the study reported SDs that were more than half of the time to relapse for the study groups.…”
Section: Discussionmentioning
confidence: 90%
See 1 more Smart Citation
“…The last study mentioned used a maximum concentration of anthralin that was 2 to 16 times less than the maximum concentration used in other studies. [12][13][14]17,18,26,40 Moreover, the study reported SDs that were more than half of the time to relapse for the study groups.…”
Section: Discussionmentioning
confidence: 90%
“…In 1 study, patients treated with the combination of clobetasol 0.05% ointment twice daily and anthralin 5% cream daily were more than twice as likely to be in remission after 23 weeks without therapy than those treated with anthralin monotherapy (90% vs 40%; P Ͻ .001). 17 Importantly, when class III or lower topical steroids were combined with anthralin, study investigators either failed to show a difference when compared with anthralin monotherapy 18 or favored anthralin monotherapy (P ϭ .011 and P ϭ .01). 19,20 Three studies comparing topical steroids with other topical agents demonstrated contradictory results.…”
Section: Resultsmentioning
confidence: 99%
“…In 1970, Farber and Harris 4 first reported the benefits of a modified dithranol regimen, alternating daily topical corticosteroid application with nightly low‐strength dithranol paste, with complete clearance within an mean treatment period of 11 days. More recently, Monk et al 5 . found a significantly faster clearance and no significant difference in relapse rate using dithranol in 0·0125% clobetasol propionate, compared with dithranol in Lassar's paste, in the treatment of chronic plaque psoriasis.…”
Section: Discussionmentioning
confidence: 99%
“…In particular, the combination with ultraviolet B treatment and, to a lesser degree, topical corticosteroids, are time‐honoured principles. However, well‐designed placebo‐controlled, prospective studies of these combination treatments are sparse with recent studies suggesting that these combinations have little therapeutic value 72–77 …”
Section: Calcineurin Inhibitorsmentioning
confidence: 99%