Anthelmintic Potential of Herbal Drugs

Nagpal, Kalpana; Pawar, Pravin; Rathi, Ritu; Gaur, Nishant; Singh, Inderbir

doi:10.1002/9781119818779.ch12

Cited by 1 publication

(1 citation statement)

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“…In this sense, Moringa oleifera is a plant that has demonstrated anthelmintic activity in ruminants, it has even been considered a candidate for the generation of new drugs, but in horses, it has not been evaluated as an antiparasitic, so scientific bases need to be generated that allow its use as a natural antiparasitic. This involves exploring various extraction methods (aqueous, methanolic, and ethanolic) to obtain bioactive compounds (tannins, flavonoids, phenolics, saponins, and alkaloids) with antiparasitic activity since there are compounds that have more affinity for some solvents than others and the antiparasitic potential depends on the extracted compounds [154]. In the same way, when defining the doses, it is necessary to consider the toxicity that each bioactive compound could cause in the animals and thus avoid adverse effects on their health, as well as evaluate in different types of parasites and larval stages and establish the mechanism of action that exerts on the control of parasites.…”

Section: Future Perspectivesmentioning

confidence: 99%

Moringa oleifera as a Natural Alternative for the Control of Gastrointestinal Parasites in Equines: A Review

Elghandour,

Maggiolino,

Vázquez-Mendoza

et al. 2023

Plants

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Studies have shown a wide variety of parasites that infect horses, causing major gastrointestinal damage that can lead to death, and although the main method of control has been synthetic anthelmintics, there are parasites that have developed resistance to these drugs. For generations, plants have been used throughout the world as a cure or treatment for countless diseases and their symptoms, as is the case of Moringa oleifera, a plant native to the western region. In all its organs, mainly in leaves, M. oleifera presents a diversity of bioactive compounds, including flavonoids, tannins, phenolic acids, saponins, and vitamins, which provide antioxidant power to the plant. The compounds with the greatest antiparasitic activity are tannins and saponins, and they affect both the larvae and the oocytes of various equine gastrointestinal parasites. Therefore, M. oleifera is a promising source for the natural control of gastrointestinal parasites in horses.

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Section: Future Perspectivesmentioning

confidence: 99%