Antenatal Three-Dimensional Printing of Aberrant Facial Anatomy

Giannopoulos²,

et al. 2019

The Laryngoscope

Objectives Medical three‐dimensional (3D) printing, the fabrication of handheld models from medical images, has the potential to become an integral part of otolaryngology–head and neck surgery (Oto‐HNS) with broad impact across its subspecialties. We review the basic principles of this technology and provide a comprehensive summary of reported clinical applications in the field. Methods Standard bibliographic databases (MEDLINE, Embase, Cumulative Index to Nursing and Allied Health Literature, Web of Science, and The Cochrane Central Registry for Randomized Trials) were searched from their inception to May 2018 for the terms: “3D printing,” “three‐dimensional printing,” “rapid prototyping,” “additive manufacturing,” “computer‐aided design,” “bioprinting,” and “biofabrication” in various combinations with the terms: “ptolaryngology,” “head and neck surgery,” and “otology.” Additional articles were identified from the references of retrieved articles. Only studies describing clinical applications of 3D printing were included. Results Of 5,532 records identified through database searching, 87 articles were included for qualitative synthesis. Widespread implementation of 3D printing in Oto‐HNS is still at its infancy. Nonetheless, it is increasingly being utilized across all subspecialties from preoperative planning to design and fabrication of patient‐specific implants and surgical guides. An emerging application considered highly valuable is its use as a teaching tool for medical education and surgical training. Conclusions As technology and training standards evolve and as healthcare moves toward personalized medicine, 3D printing is emerging as a key technology in patient care in Oto‐HNS. Treating physicians and surgeons who wish to stay abreast of these developments will benefit from a fundamental understanding of the principles and applications of this technology. Laryngoscope, 129:2045–2052, 2019

Section: Resultsmentioning

confidence: 99%

Clinical applications of three‐dimensional printing in otolaryngology–head and neck surgery: A systematic review

Giannopoulos²,

et al. 2019

The Laryngoscope

“…Printed 3D specimens have been used to train specialists and clinicians (e.g., Adams et al, ; VanKoevering et al, ; Li et al, ; Loke et al, ), and to plan a range of surgical procedures in areas as diverse as hepatobiliary intervention (Javan and Zeman, ), nephrectomy (Golab et al, ), treatment of osteogenesis imperfecta (Eisenmenger et al, ), and both cardiac (Bartel et al, ) and spinal surgery (Cramer et al, ). This research has highlighted the potential for 3D printing to equally contribute to the development of competency in fetal and early childhood surgery, particularly as a high skill field of surgery, and where the opportunities for skills enhancement may be very limited.…”

Section: Discussionmentioning

confidence: 99%

Three‐Dimensional Printing of Archived Human Fetal Material for Teaching Purposes

Young

Quayle

Adams

et al. 2018

Anatomical Sciences Ed

The practical aspect of human developmental biology education is often limited to the observation and use of animal models to illustrate developmental anatomy. This is due in part to the difficulty of accessing human embryonic and fetal specimens, and the sensitivity inherent to presenting these specimens as teaching materials. This report presents a new approach using three-dimensional (3D) printed replicas of actual human materials in practical classes, thus allowing for the inclusion of accurate examples of human developmental anatomy in the educational context. A series of 3D prints have been produced from digital data collected by computed tomography (CT) imaging of an archived series of preserved human embryonic and fetal specimens. The final versions of 3D prints have been generated in a range of single or multiple materials to illustrate the progression of human development, including the development of internal anatomy. Furthermore, multiple copies of each replica have been printed for large group teaching. In addition to the educational benefit of examining accurate 3D replicas, this approach lessens the potential for adverse student reaction (due to cultural background or personal experience) to observing actual human embryonic/fetal anatomical specimens, and reduces the potential of damage or loss of original specimens. This approach, in combination with ongoing improvements in the management and analysis of digital data and advances in scanning technology, has enormous potential to allow embryology students access to both local and international collections of human gestational material. Anat Sci Educ 00: 000-000. © 2018 American Association of Anatomists.

“…3D printing has found a number of applications across many of the surgical subspecialties, including mandibular reconstruction [1], as customised external fixators in orthopaedic surgery [2] and for the peri-operative planning of interventional neuroradiology [3]. For airway surgery, a 3D printed model of the craniofacial anatomy of a fetus was produced from an in-utero magnetic resonance imaging (MRI) scan, enabling a multidisciplinary decision to deliver the neonate without performing a ex-uterointrapartum treatment (EXIT) procedure [4]. 3D printing has also been used in the planning [5] and manufacture [6] of customised stents for placement within the bronchial tree.…”

Section: Discussionmentioning

confidence: 99%

3D printing as an adjunct to complex airway assessment

et al. 2016

A patient with known neurofibromatosis type 1 (NF1) who presented for urgent spinal surgery was predicted to have a difficult airway due to a large craniofacial neurofibroma. From a three dimensional (3D) computed tomography (CT) reconstruction of his airway, a 3D printed model was manufactured. The 3D model aided the peri-operative planning of the patient's airway management, and is the first published report of its kind.