Antenatal lower genital tract infection screening and treatment programs for preventing preterm delivery

Self-Testing of Vaginal pH to Prevent Preterm Delivery

“…The effectiveness of annual screening by a (specialist) physician for bacterial vaginosis is under debate. A prospective, randomized, controlled study (3) on the usefulness of screening by a general practitioner, and the Cochrane Report that was based on this study (4), demonstrate a risk reduction (RR 0.6; 95% CI: 0.41-0.75). However, there are methodological limitations, for example in the comparability of the study groups (4,5), and international institutions recommend against the screening of asymptomatic pregnant women with an average risk profile (6,7).…”

Self-Testing of Vaginal pH to Prevent Preterm Delivery

“…The effectiveness of annual screening by a (specialist) physician for bacterial vaginosis is under debate. A prospective, randomized, controlled study (3) on the usefulness of screening by a general practitioner, and the Cochrane Report that was based on this study (4), demonstrate a risk reduction (RR 0.6; 95% CI: 0.41-0.75). However, there are methodological limitations, for example in the comparability of the study groups (4,5), and international institutions recommend against the screening of asymptomatic pregnant women with an average risk profile (6,7).…”

Effect of probiotics on vaginal health in pregnancy. EFFPRO, a randomized controlled trial

“…6,7 Treating BV with antibiotics, however, although it resolved the symptoms of BV, did not prevent PD. 8,9 Assuming that the course of events that ultimately results in PD starts well before the manifestation of BV can be diagnosed, early screening for changes in vaginal pH has been suggested but showed no consistent effect on PD rates. 10 So far, studies that have aimed to show efficacy of probiotics in the prevention of PD have been underpowered.…”

Evaluation of treatment efficacy and prevention of complications in pregnant women with vaginal infections

“…Воспаление приводит к образованию в организме эндогенных токсинов, при этом развивается синдром эндогенной интоксикации (ЭИ), параметры которых свидетельствуют об активности инфекционного процесса и, следовательно, о риске преждевременных родов [2]. Своевременная санация, применение пробиотиков при ВИ беременных, осложнённой угрожающими преждевременными родами (УПР) предотвращает инфицирование плода, и является профилактикой преждевременных родов [2]. В последнее время особое внимание уделяется использованию фитопрепаратов вместо синтетических [3].…”

Self-Testing of Vaginal pH to Prevent Preterm Delivery

“…The effectiveness of annual screening by a (specialist) physician for bacterial vaginosis is under debate. A prospective, randomized, controlled study (3) on the usefulness of screening by a general practitioner, and the Cochrane Report that was based on this study (4), demonstrate a risk reduction (RR 0.6; 95% CI: 0.41-0.75). However, there are methodological limitations, for example in the comparability of the study groups (4,5), and international institutions recommend against the screening of asymptomatic pregnant women with an average risk profile (6,7).…”

Effect of probiotics on vaginal health in pregnancy. EFFPRO, a randomized controlled trial

“…6,7 Treating BV with antibiotics, however, although it resolved the symptoms of BV, did not prevent PD. 8,9 Assuming that the course of events that ultimately results in PD starts well before the manifestation of BV can be diagnosed, early screening for changes in vaginal pH has been suggested but showed no consistent effect on PD rates. 10 So far, studies that have aimed to show efficacy of probiotics in the prevention of PD have been underpowered.…”

Evaluation of treatment efficacy and prevention of complications in pregnant women with vaginal infections

“…Воспаление приводит к образованию в организме эндогенных токсинов, при этом развивается синдром эндогенной интоксикации (ЭИ), параметры которых свидетельствуют об активности инфекционного процесса и, следовательно, о риске преждевременных родов [2]. Своевременная санация, применение пробиотиков при ВИ беременных, осложнённой угрожающими преждевременными родами (УПР) предотвращает инфицирование плода, и является профилактикой преждевременных родов [2]. В последнее время особое внимание уделяется использованию фитопрепаратов вместо синтетических [3].…”

Self-Testing of Vaginal pH to Prevent Preterm Delivery

“…The effectiveness of annual screening by a (specialist) physician for bacterial vaginosis is under debate. A prospective, randomized, controlled study (3) on the usefulness of screening by a general practitioner, and the Cochrane Report that was based on this study (4), demonstrate a risk reduction (RR 0.6; 95% CI: 0.41-0.75). However, there are methodological limitations, for example in the comparability of the study groups (4,5), and international institutions recommend against the screening of asymptomatic pregnant women with an average risk profile (6,7).…”

Effect of probiotics on vaginal health in pregnancy. EFFPRO, a randomized controlled trial

“…6,7 Treating BV with antibiotics, however, although it resolved the symptoms of BV, did not prevent PD. 8,9 Assuming that the course of events that ultimately results in PD starts well before the manifestation of BV can be diagnosed, early screening for changes in vaginal pH has been suggested but showed no consistent effect on PD rates. 10 So far, studies that have aimed to show efficacy of probiotics in the prevention of PD have been underpowered.…”

Evaluation of treatment efficacy and prevention of complications in pregnant women with vaginal infections

“…Воспаление приводит к образованию в организме эндогенных токсинов, при этом развивается синдром эндогенной интоксикации (ЭИ), параметры которых свидетельствуют об активности инфекционного процесса и, следовательно, о риске преждевременных родов [2]. Своевременная санация, применение пробиотиков при ВИ беременных, осложнённой угрожающими преждевременными родами (УПР) предотвращает инфицирование плода, и является профилактикой преждевременных родов [2]. В последнее время особое внимание уделяется использованию фитопрепаратов вместо синтетических [3].…”