2020
DOI: 10.2147/jaa.s289592
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Abstract: Purpose Fractional exhaled nitric oxide (FENO) reflects eosinophilic inflammation of the airways. However, the significance of longitudinal assessment of FENO, including its variability, in the clinical course of severe asthma remains unclear. The aim of this study is to examine the association between long-term changes in FENO and the development of exacerbations in severe asthma. Patients and Methods Among the severe asthma patients enrolled in the Hokkaido Severe Ast…

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