Animal Models of Immunity to Female Genital Tract Infections and Vaccine Development

Kaushic, Charu; Jerse, Ann E.; Beagley, Kenneth W.

doi:10.1016/b978-0-12-415847-4.00107-5

Cited by 4 publications

(1 citation statement)

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“…The acute phase of an infection of C. muridarum in female mice usually takes 30 days to resolve, and symptoms such as hydrosalpinx often appear in some infected mice two to three months later. The C. muridarum -infected mice are later immune to subsequent reinfection of the same pathogen after the disease is resolved [145,146]. C. muridarum infection in male mice causes urethritis without impairing male infertility or sperm quality [147].…”

Section: Introductionmentioning

confidence: 99%

Chlamydiaceae: Diseases in Primary Hosts and Zoonosis

et al. 2019

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Bacteria of the Chlamydiaceae family are a type of Gram-negative microorganism typified by their obligate intracellular lifestyle. The majority of the members in the Chlamydiaceae family are known pathogenic organisms that primarily infect the host mucosal surfaces in both humans and animals. For instance, Chlamydia trachomatis is a well-known etiological agent for ocular and genital sexually transmitted diseases, while C. pneumoniae has been implicated in community-acquired pneumonia in humans. Other chlamydial species such as C. abortus, C. caviae, C. felis, C. muridarum, C. pecorum, and C. psittaci are important pathogens that are associated with high morbidities in animals. Importantly, some of these animal pathogens have been recognized as zoonotic agents that pose a significant infectious threat to human health through cross-over transmission. The current review provides a succinct recapitulation of the characteristics as well as transmission for the previously established members of the Chlamydiaceae family and a number of other recently described chlamydial organisms.

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Section: Introductionmentioning

confidence: 99%